Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R F, Bruns"'
Autor:
L. C. S. Bussamra, R. F. Bruns, C. G. V. Murta, R. M. Santana, P. S. Cossi, A. F. Moron, Eduardo Cordioli
Publikováno v:
Ultrasound in Obstetrics and Gynecology. 28:519-520
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::293405f699652e4af5670436983b8035
https://doi.org/10.1002/uog.3418
https://doi.org/10.1002/uog.3418
Autor:
B D, Gitter, R F, Bruns, J J, Howbert, D C, Waters, P G, Threlkeld, L M, Cox, J A, Nixon, K L, Lobb, N R, Mason, P W, Stengel
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(2)
LY303870 [(R)-1-[N-(2-methoxybenzyl)acetylamino]-3-(1H-indol-3-yl)-2-[N-(2-(4- (piperidin-1-yl)piperidin-1-yl)acetyl)amino]propane] is a new, potent and selective nonpeptide neurokinin-1 (NK-1) receptor antagonist. LY303870 bound selectively and with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c5c0e91e949c65a5596c944f83cb07b
https://pubmed.ncbi.nlm.nih.gov/7473161
https://pubmed.ncbi.nlm.nih.gov/7473161
Publikováno v:
Circulation research. 75(6)
The 2-amino-3-benzoylthiophene derivative PD 81,723 is an allosteric enhancer of agonist binding to brain A1 adenosine receptors. One aim of this study was to characterize and contrast the effects of PD 81,723 on the A1 receptor-mediated negative dro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfb020b40d6c925766265d178b08a19
https://pubmed.ncbi.nlm.nih.gov/7955150
https://pubmed.ncbi.nlm.nih.gov/7955150
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 266(2)
The drug (2-amino-4,5-dimethyl-3-thienyl)-[3(trifluoromethyl)-phenyl]methanone (PD 81,723) has been shown to enhance allosterically A1 adenosine receptor binding in brain membranes. The objective of this study was to determine the specificity and sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ad2f425f853a468f37559d2c79afad1
https://pubmed.ncbi.nlm.nih.gov/8355194
https://pubmed.ncbi.nlm.nih.gov/8355194
Publikováno v:
The American journal of physiology. 264(3 Pt 2)
Adenosine, a locally released and rapidly metabolized nucleoside, protects the heart from damage during ischemia by reducing oxygen demand and increasing oxygen supply. The aminothiophene derivative (2-amino-4,5-dimethylthien-3-yl)[3-(trifluoromethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05285a6480319a8e134cd0c584b7bad
https://pubmed.ncbi.nlm.nih.gov/8456969
https://pubmed.ncbi.nlm.nih.gov/8456969
Autor:
R F, Bruns, J H, Fergus
Publikováno v:
Molecular pharmacology. 38(6)
Several 2-amino-3-benzoylthiophenes were found to increase the binding of [3H]N6-cyclohexyladenosine to A1 adenosine receptors in rat brain membranes. Concentration-response curves were bell-shaped, with up to 45% stimulation of binding at 10 microM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e962d0ca3ca5591c974e8dc7fc71d443
https://pubmed.ncbi.nlm.nih.gov/2174510
https://pubmed.ncbi.nlm.nih.gov/2174510
Autor:
R F, Bruns, J H, Fergus, L L, Coughenour, G G, Courtland, T A, Pugsley, J H, Dodd, F J, Tinney
Publikováno v:
Molecular pharmacology. 38(6)
The structural requirements for stimulation of adenosine A1 agonist binding by 2-amino-3-benzoylthiophenes and related compounds were investigated. Slowing of the dissociation of [3H]N6cyclohexyladenosine binding was used as a specific measure of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd7395f29ae4363684ced9d8806c98ba
https://pubmed.ncbi.nlm.nih.gov/2250667
https://pubmed.ncbi.nlm.nih.gov/2250667
Autor:
D T, Dudley, R L, Panek, T C, Major, G H, Lu, R F, Bruns, B A, Klinkefus, J C, Hodges, R E, Weishaar
Publikováno v:
Molecular pharmacology. 38(3)
Specific binding sites for angiotensin II were identified in the rabbit adrenal gland and uterus and in the rat liver and were divided into two subclasses based on inhibition by nonpeptide ligands. Peptide ligands affected binding equally in all thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c96085dc59f0ee020d9847af15c0e254
https://pubmed.ncbi.nlm.nih.gov/2402226
https://pubmed.ncbi.nlm.nih.gov/2402226
Autor:
R. F. Bruns
Publikováno v:
Purines in Cellular Signaling ISBN: 9781461279969
An important milestone in adenosine research was the discovery by Sattin and Rall in 1970 that theophylline and other methylxanthines could block responses to adenosine. With the availability of competitive adenosine antagonists, it was possible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::364a57ddacc35eb53deefba8d6518145
https://doi.org/10.1007/978-1-4612-3400-5_21
https://doi.org/10.1007/978-1-4612-3400-5_21
Autor:
R. F. Bruns, C. G. V. Murta, Marina Maccagnano Zamith, P. S. Cossi, A. F. Moron, L. F. A. Gonçalves
Publikováno v:
Ultrasound in Obstetrics and Gynecology. 28:532-532
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aec4816274281ba25a1afacd5ab14f6
https://doi.org/10.1002/uog.3471
https://doi.org/10.1002/uog.3471