Zobrazeno 1 - 10
of 171
pro vyhledávání: '"R Elwyn Isaac"'
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1132 (2023)
A novel protein, PID-5, has been shown to be a requirement for germline immortality and has recently been implicated in RNA-induced epigenetic silencing in the Caenorhabditis elegans embryo. Importantly, it has been shown to contain both an eTudor an
Externí odkaz:
https://doaj.org/article/83983e4888394cac85b05a12fc560929
Autor:
Nicola Silva, Maikel Castellano-Pozo, Kenichiro Matsuzaki, Consuelo Barroso, Monica Roman-Trufero, Hannah Craig, Darren R Brooks, R Elwyn Isaac, Simon J Boulton, Enrique Martinez-Perez
Publikováno v:
PLoS Genetics, Vol 18, Iss 1, p e1010025 (2022)
Genotoxic stress during DNA replication constitutes a serious threat to genome integrity and causes human diseases. Defects at different steps of DNA metabolism are known to induce replication stress, but the contribution of other aspects of cellular
Externí odkaz:
https://doaj.org/article/a96ac9391b0141f5855e9de298dde95f
Autor:
Charlotte E. Pugsley, R. Elwyn Isaac, Nicholas. J. Warren, Juliette S. Behra, Kaat Cappelle, Rosa Dominguez-Espinosa, Olivier. J. Cayre
Publikováno v:
Biomacromolecules. 23:2362-2373
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ef02b5a4e4fd2cd46d20cc5d5880b01
https://doi.org/10.1021/acs.biomac.2c00136
https://doi.org/10.1021/acs.biomac.2c00136
Publikováno v:
Polymer Chemistry. 13:5707-5717
We herein report the synthesis and characterisation of linear ABC triblock copolymers, investigation of their self-assembly in aqueous solution, and complexation with and protection of double stranded-RNA (dsRNA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02a4d202d7645ab4ca2ed29ba150bfb2
https://doi.org/10.1039/d2py00914e
https://doi.org/10.1039/d2py00914e
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201294 (2018)
Drosophila suzukii or spotted wing Drosophila is an economically important pest which can have a devastating impact on soft and stone fruit industries. Biological pesticides are being sought as alternatives to synthetic chemicals to control this inva
Externí odkaz:
https://doaj.org/article/b6e933b835214755a674d87380699ce8
Autor:
Shalini Iyer, Penelope J. La-Borde, Karl A.P. Payne, Mark R. Parsons, Anthony J. Turner, R. Elwyn Isaac, K. Ravi Acharya
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 292-302 (2015)
Eukaryotic aminopeptidase P1 (APP1), also known as X‐prolyl aminopeptidase (XPNPEP1) in human tissues, is a cytosolic exopeptidase that preferentially removes amino acids from the N‐terminus of peptides possessing a penultimate N‐terminal proli
Externí odkaz:
https://doaj.org/article/a81b952de5dc4dc08fa330f7521a86c9
Autor:
Charlotte E. Pugsley, R. Elwyn Isaac, Nicholas. J. Warren, Martin Stacey, Kaat Cappelle, Rosa Dominguez-Espinosa, Olivier. J. Cayre
Chemical insecticides are an important tool to control damaging pest infestations. However, lack of species specificity, the rise of resistance to these pesticides and the demand for biological alternatives with improved ecotoxicity profiles means th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07300a752a1e406fceb993ab14d1cabd
https://doi.org/10.21203/rs.3.rs-2272882/v1
https://doi.org/10.21203/rs.3.rs-2272882/v1
Autor:
Caroline S Gough, Grace M Fairlamb, Petra Bell, Ronald J Nachman, Neil Audsley, R Elwyn Isaac
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188021 (2017)
Neuropeptides play an important role in the regulation of feeding in insects and offer potential targets for the development of new chemicals to control insect pests. A pest that has attracted much recent attention is the highly invasive Drosophila s
Externí odkaz:
https://doaj.org/article/2e308b2b67c043c692ec805bfeb695a2
Publikováno v:
Journal of Medicinal Chemistry. 64:1763-1785
Malaria poses a significant threat to approximately half of the world's population with an annual death toll close to half a million. The emergence of resistance to front-line antimalarials in the most lethal human parasite species, Plasmodium falcip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71f3c2a6c2ae294851a9d7e072ee9ae2
https://doi.org/10.1021/acs.jmedchem.0c01721
https://doi.org/10.1021/acs.jmedchem.0c01721
Autor:
null Gyles E. Cozier, null Emma C. Newby, null Sylva L. U. Schwager, null R. Elwyn Isaac, null Edward D. Sturrock, null K. Ravi Acharya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74439a198717789b50896599edf31b12
https://doi.org/10.1111/febs.16543/v2/response1
https://doi.org/10.1111/febs.16543/v2/response1