Zobrazeno 1 - 10
of 50
pro vyhledávání: '"R E Vestal"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 10, Pp 2035-2048 (1997)
In this paper we describe a sterol-independent regulation of low density, lipoprotein receptor (LDLR) transcription by the cytokine oncostatin M (OM) in HepG2 cells. We show that OM-induced expression is independent of cholesterol regulation and occu
Externí odkaz:
https://doaj.org/article/2b09c6a99d684fb899b3a41711b1c9d2
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:2948-2954
Abstract We have investigated liver LDL receptor mRNA expression in nontransgenic, human cholesteryl ester transfer protein (CETP) transgenic, and human apolipoprotein (Apo) B/CETP double transgenic mice fed a normal chow diet and a high fat, high ch
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 10, Pp 2035-2048 (1997)
In this paper we describe a sterol-independent regulation of low density, lipoprotein receptor (LDLR) transcription by the cytokine oncostatin M (OM) in HepG2 cells. We show that OM-induced expression is independent of cholesterol regulation and occu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H307-H315
The purpose of this study was to compare the responses of isolated hearts of the diving muskrat with the nondividing guinea pig (GP) to determine the contribution of adenosine (ADO) to the profound bradycardia that was seen in isolated muskrat hearts
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(2)
To characterize age-related changes in beta-adrenergic responsiveness and to test the hypothesis that an increase in the effects of adenosine contribute to impaired beta-adrenergic responsiveness, Fischer 344 rat right atria (RA), left atria (LA), an
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(2)
Mexiletine, lidocaine, and tocainide are class IB antiarrhythmic drugs that are used for the treatment of ventricular arrhythmias and are known to inhibit drug metabolism. The objectives of this study were to characterize the inhibitory effects of me
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(2)
The 2-amino-3-benzoylthiophene PD 81,723 has been shown to exhibit allosteric enhancement of adenosine A1 receptor binding and function. The aim of this study was to clarify the mechanism of this effect using membranes purified from rat brain and Chi
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(10)
Flavonoids are a class of dietary phytochemicals that modulate various biological activities. The effects of flavone and five hydroxylated derivatives on the methoxyresorufin O-demethylase activity catalyzed by cDNA-expressed human cytochromes P450 (
Autor:
R E, Vestal
Publikováno v:
Clinical pharmacology and therapeutics. 63(4)
Autor:
R E, Vestal
Publikováno v:
Cancer. 80(7)
Research on aging and pharmacology in humans has been termed geriatric clinical pharmacology, which is an established subdiscipline within the broad field of clinical pharmacology. This article reviews information relevant to clinical cancer research