Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R E Swann"'
Autor:
E. Thomson, John McLauchlan, Arvind H. Patel, Sarah Cole, Peter R. Mills, R E Swann, Vanessa M. Cowton, Mark W. Robinson, Stephen T. Barclay
Publikováno v:
Journal of Virology. 90:4530-4543
During hepatitis C virus (HCV) infection, broadly neutralizing antibody (bNAb) responses targeting E1E2 envelope glycoproteins are generated in many individuals. It is unclear if these antibodies play a protective or a pathogenic role during chronic
Autor:
John McLauchlan, Elihu Aranday-Cortes, Jolanda M. P. Liefhebber, Arvind H. Patel, Alex Sigruener, Stephen T. Barclay, Derek Gatherer, R E Swann, Mark W. Robinson, Peter R. Mills, Ana da Silva Filipe
Publikováno v:
Liver International
Background: Chronic hepatitis C virus (HCV) infection of the liver with either genotype 1 or genotype 3 gives rise to distinct pathologies and the two viral genotypes respond differently to antiviral therapy.\ud \ud Methods: To understand these clini
Autor:
R E, Swann, P, Mandalou, M W, Robinson, M M, Ow, S K H, Foung, J, McLauchlan, A H, Patel, M E, Cramp
Publikováno v:
Journal of Viral Hepatitis
Summary Injection drug users uninfected by hepatitis C virus (HCV) despite likely repeated exposure through high‐risk behaviour are well documented. Factors preventing infection in these individuals are incompletely understood. Here, we looked for
Autor:
R E Swann, Peter R. Mills, Arvind H. Patel, Stephen T. Barclay, John McLauchlan, Mark W. Robinson, Dagmara McGuinness, Paul G. Shiels
Publikováno v:
Aging Cell. 12:1141-1143
Chronic hepatitis C virus infection (C-HC) is associated with higher mortality arising from hepatic and extrahepatic disease. This may be due to accelerated biological aging; however, studies in C-HC have thus far been based solely on telomere length
Autor:
Vanessa M. Cowton, John McLauchlan, Peter R. Mills, Arvind H. Patel, R E Swann, Mark W. Robinson, Stephen T. Barclay
Publikováno v:
Gut. 64:A11.1-A11
Introduction HCV remains a major cause of liver morbidity and mortality worldwide. The capacity of HCV to rapidly mutate poses a challenge for immunisation as a preventative strategy. Increasing evidence suggests that the breadth of anti-HCV antibody
Autor:
Stephen T. Barclay, Rachael Bashford-Rogers, R E Swann, Mark W. Robinson, Paul Kellam, Arvind H. Patel, John McLauchlan, Peter R. Mills
Publikováno v:
Gut. 64:A110.1-A110
Introduction In addition to causing liver injury, hepatitis C virus (HCV) is closely associated with clonal B-cell pathologies such as cryogloglobulinaemia. 1 The virus is also capable of evading control by antibody responses. 2 Understanding the mec
Autor:
M Priest, John McLauchlan, R E Swann, Arvind H. Patel, Mark W. Robinson, Peter R. Mills, Stephen T. Barclay
Publikováno v:
Gut. 62:A184.3-A185
Introduction Hepatitis C virus (HCV) infection is the most common cause of cryoglobulinaemia – a clonal B cell disorder characterised by precipitation of antibody aggregates on serum cooling. This can lead to vasculitic symptoms and complications i
Publikováno v:
Gut. 62:A46.1-A46
Introduction Simulation is increasingly being advocated to enhance training in complex technical skills such as endoscopy. While a growing body of evidence suggests simulation use within a study context can improve technical and non-technical skills
Publikováno v:
Gut. 62:A94.2-A95
Introduction Hepatitis C (HCV) was first characterised in 1989 and most UK sufferers are infected in early adulthood. While a cirrhosis rate of 20% over 20 years is often quoted, life-long outcomes and factors predicting these are not fully defined.
Publikováno v:
Gut. 61:A410.1-A410
Introduction Cystic fibrosis (CF) associated liver disease affects up to 41% of CF sufferers and may progress to cirrhosis with associated complications. 1 Diagnosis is frequently made without biopsy. A recent study evaluated the use of fibroscan in