Zobrazeno 1 - 10
of 16
pro vyhledávání: '"R E Hartnagel"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(2)
This study was conducted to evaluate the pharmacokinetic parameters of absorption, distribution, metabolism, and excretion (ADME) of the personal insect repellent N,N-diethyl-m-toluamide (DEET) after oral or dermal administration of [14C]DEET in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c57715fea56a7c911bb569406aa0f0f
https://pubmed.ncbi.nlm.nih.gov/8742226
https://pubmed.ncbi.nlm.nih.gov/8742226
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 14(1)
The purpose of this study was to assess the embryotoxic, fetotoxic, and teratogenic potential of METASYSTOX-R (MSR) in the rat. Furthermore, the study was designed to determine if maternally toxic doses of MSR altered fetal brain acetylcholinesterase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108c8a6e4e2fafc079bf7dcf97918ad4
https://pubmed.ncbi.nlm.nih.gov/2307312
https://pubmed.ncbi.nlm.nih.gov/2307312
Autor:
B Herbold, G. R. Clemens, Robert L. Kowalski, R E Hartnagel, K C Norbury, D Abrutyn, G Schlueter, J W Kille, M. C. Porter
Publikováno v:
Scandinavian Journal of Gastroenterology. 24:42-45
The toxicity of rioprostil was extensively investigated. Studies in rodents, dogs and monkeys indicate a low order of acute toxicity. Oral subchronic and chronic toxicity studies in rats and dogs produce effects that would be expected based on the ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ceb05e8cb8bfa1f6eac81df4ebc5b9
https://doi.org/10.3109/00365528909091184
https://doi.org/10.3109/00365528909091184
Publikováno v:
Australian and New Zealand Journal of Medicine. 6:48-53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be0ea7e4bbbba8746e58563c8ceafff3
https://doi.org/10.1111/j.1445-5994.1976.tb03676.x
https://doi.org/10.1111/j.1445-5994.1976.tb03676.x
Autor:
M. C. Porter, J. J. Bare, W.E. Halliwell, R. E. Hartnagel, Robert L. Kowalski, D.N. Kitchen, G. R. Clemens
Publikováno v:
Toxicological Sciences. 3:478-482
The narcotic antagonist TR5379M had po LD50 values of 365 and 750 mg/kg and iv LD50 values of 35.0 and 22.3 mg/kg in the mouse and rat, respectively. Subchronic (one month) po administration to rats at 40, 120, or 400 mg/kg/day and to cynomolgus monk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5245beb48541b55248c5dd5591ddec
https://doi.org/10.1093/toxsci/3.5.478
https://doi.org/10.1093/toxsci/3.5.478
Autor:
V, Jasty, J J, Bare, J R, Jamison, M C, Porter, R L, Kowalski, G R, Clemens, G E, Jackson, R E, Hartnagel
Publikováno v:
Laboratory animal science. 36(1)
Pathologic examination of sternums from young growing rats revealed a number of skeletal lesions involving both cartilage and bone elements. Degeneration or aseptic necrosis of the intersternebral cartilage was a frequent finding in most rats that we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e63f874192e309a33dbeab69751af20c
https://pubmed.ncbi.nlm.nih.gov/3959534
https://pubmed.ncbi.nlm.nih.gov/3959534
Autor:
L B, Katz, R J, Capetola, D C, Argentieri, L E, Moore, T, Genna, M C, Porter, V, Jasty, R E, Hartnagel, D, Abrutyn, D A, Shriver
Publikováno v:
The Journal of rheumatology. 13(5)
Gastrointestinal irritation is the most significant side effect in patients chronically taking nonsteroidal antiinflammatory drugs (NSAID) for treatment of arthritic conditions. Rioprostil, a primary alcohol prostaglandin E1 analog, prevents gastric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc10a95223136e46324c17769a75e9a8
https://pubmed.ncbi.nlm.nih.gov/3102726
https://pubmed.ncbi.nlm.nih.gov/3102726
Publikováno v:
Australian and New Zealand journal of medicine. 6
Using a compound analgesic mixture, it was found that renal pathology could be produced in rats if the analgesic mixture was administered as a concentrated aqueous suspension, but that development of renal pathology was not favored by hot, dry enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8a5d547799f3586fdfc3e26b0a9d829
https://pubmed.ncbi.nlm.nih.gov/1070998
https://pubmed.ncbi.nlm.nih.gov/1070998
Autor:
Robert L. Kowalski, R. E. Hartnagel, G. R. Clemens, Emma H. Fonseca, V. Jasty, M. C. Porter, J. J. Bare
Publikováno v:
Veterinary pathology. 21(1)
Histologic, histochemical, and electron microscopic studies of generalized ceroid-lipofuscinosis in a cynomolgus monkey are presented. Histologically, a wide variety of tissue cells contained numerous bright eosinophilic intracytoplasmic granules tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f69fde1f24d417f74889d7f83e652d2
https://pubmed.ncbi.nlm.nih.gov/6538717
https://pubmed.ncbi.nlm.nih.gov/6538717