Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R E, Squibb"'
Publikováno v:
Bondy, SC; Agrawal, AK; & Squibb, RE. (1981). The effects of acrylamide treatment upon the dopamine receptor. Toxicol Appl Pharmacol, 58. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/06d4t4j4
The binding of tritiated spiroperidol to striatal membranes prepared from acrylamide-treated male 6-week-old rats and matched controls has been studied. This binding has high-affinity characteristics and is stereospecific and reversible. Equilibrium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845992773f7868fd665384a6e20fd388
https://doi.org/10.1016/0041-008x(81)90119-8
https://doi.org/10.1016/0041-008x(81)90119-8
Publikováno v:
Regulatory Peptides. 2:347-352
Administration of monosodium glutamate (MSG) during the neonatal period in rats produced differential effects on the contents of various neuropeptides in the hypothalamus: beta-endorphin (beta-E) level was reduced by 70% while substance P (SP), neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9fbfa77d85cd6503d0bcb19d563ca26
https://doi.org/10.1016/0167-0115(81)90016-1
https://doi.org/10.1016/0167-0115(81)90016-1
Publikováno v:
Toxicology and Applied Pharmacology. 55:188-197
The repeated administration of triethyl tin bromide (TET) (0, 1.0, 2.0, and 3.0 mg/kg, po) to male rats produced dose- and time-dependent reductions in body weights and food and water consumption. Tests showed decreases in fore- and hindlimb grip str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b57df41260d64f496ab1bcbcdda923
https://doi.org/10.1016/0041-008x(80)90235-5
https://doi.org/10.1016/0041-008x(80)90235-5
Publikováno v:
Neurotoxicology. 2(3)
On days 1-15 postpartum male and female Sprague-Dawley derived CD strain pups were dosed sc with either L-glutamic acid (MSG) (2-3.5 mg/g), 13% or 0.85% saline and tested at 67 and 102 days of age. At both periods, the body weights of MSG exposed mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5396657939f398b94ad343d3cefbe804
https://pubmed.ncbi.nlm.nih.gov/7199686
https://pubmed.ncbi.nlm.nih.gov/7199686
Autor:
Stephen C. Bondy, R. E. Squibb, Coral A. Lamartiniere, George A. Mason, John S. Hong, Charles B. Nemeroff
Publikováno v:
Neuroendocrinology. 33(5)
Serum levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin, estradiol-17 beta and testosterone were determined in adult rats that were treated in the neonatal period with monosodium L-glutamate (MSG) which has previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5784860406b5705eb9343169c90a990
https://pubmed.ncbi.nlm.nih.gov/6795522
https://pubmed.ncbi.nlm.nih.gov/6795522
Publikováno v:
Bondy, SC; Agrawal, AK; Seth, PK; Squibb, RE; Tilson, HA; & Uphouse, LL. (1981). Neurotransmitter receptors in brain regions of acrylamide-treated rats. I. Effects of a single exposure to acrylamide. Pharmacol Biochem Behav, 14. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1st4266s
A single oral dose of acrylamide (25 or 50 mg/kg) increased the level of striatal 3H-spiroperidol binding in six week old male rats. This enhanced dopamine receptor activity was specific since treatment caused no significant changes in glycine, serot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a32b100e0029232816ec19315719cf7
http://www.escholarship.org/uc/item/1st4266s
http://www.escholarship.org/uc/item/1st4266s
Autor:
R. E. Squibb, Hugh A. Tilson
Publikováno v:
Physiologybehavior. 26(4)
A standard running wheel apparatus was modified to measure home cage crossings, wheel turn activity, and activities related to food and water ingestion. The apparatus was designed to provide continuous measurements using transistor-integrated electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62739a5b920551e3c5d5bf7aadc58516
https://pubmed.ncbi.nlm.nih.gov/7267764
https://pubmed.ncbi.nlm.nih.gov/7267764
Publikováno v:
Neurobehavioral toxicology and teratology. 5(3)
2,4-Dichlorophenoxyacetic acid (2,4-D), an organic acid commonly used as a herbicide, was assessed for behavioral and neurological toxicity in male Fischer-344 rats. When given by gavage twice weekly for 5 weeks, 2,4-D produced a significant increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c997e95f697abd315e4d332fca4cb3b
https://pubmed.ncbi.nlm.nih.gov/6877474
https://pubmed.ncbi.nlm.nih.gov/6877474
Publikováno v:
Toxicology and applied pharmacology. 58(3)
Pregnant Fischer 344 strain rats were exposed by gavage to 20 mg acrylamide/kg body wt/day on 10 successive days (Days 6 to 17 of gestation) for a total cumulative dose of 200 mg/kg. On Day 1 of age, the pups were pooled into two groups (treated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e657280720959392a207b97f6edba291
https://pubmed.ncbi.nlm.nih.gov/7245209
https://pubmed.ncbi.nlm.nih.gov/7245209
Publikováno v:
Neurotoxicology. 3(2)
Male and female Fischer 344 rat pups were exposed to either DMSO or chlordecone (Kepone) by s.c. injection on day 4 postnatally. Chlordecone had transient effects on body weights and resulted in precocial vaginal opening (vaginas open at day 21 of ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a85d54a5171fdbb1060a97bc6242132
https://pubmed.ncbi.nlm.nih.gov/6186964
https://pubmed.ncbi.nlm.nih.gov/6186964