Zobrazeno 1 - 10
of 52
pro vyhledávání: '"R E, Sage"'
Autor:
R. E. Sage, J.E. Norman, Dusan Kotasek, A. Gregg, P. Charles, B.M. Dale, K.M. Shepherd, J. Futter
Publikováno v:
Clinical & Laboratory Haematology. 13:25-32
Thirty one peripheral blood stem cell mobilizations using cyclophosphamide, followed by leucapheresis, were performed in 25 patients with a variety of haematological malignancies. Cyclophosphamide at doses ranging from 0.25 g/M2/day x 4 days to 4 g/M
Publikováno v:
Blood. 97:3633-3639
Loss of A, B, and H antigens from the surface of red blood cells has been a recurrent observation in patients with hematologic malignancy, particularly those malignancies in which the myeloid lineage is involved. To better understand this phenomenon,
Autor:
Peter J. Hewett, Jennie L. Finch, Alexander Dobrovic, Dusan Kotasek, Jacqueline D. Nuttall, R. E. Sage, Jennifer E. Hardingham
Publikováno v:
International Journal of Cancer. 89:8-13
In colorectal cancer (CRC), a proportion of patients with early stage disease still die of metastatic or recurrent disease within 5 years of "curative" resection. Detection of carcinoma cells in the peripheral circulation at presentation may identify
Autor:
Alexander Dobrovic, R B Dymock, R. E. Sage, Jennifer E. Hardingham, David Roder, Ian C. Roberts-Thomson, W J Butler
Publikováno v:
Europe PubMed Central
Background—Somatic mutations in K-ras and TP53 may be associated with both acetylator status and prognosis in colorectal cancer.Aims—To determine whether cancers with somatic mutations are more frequent in fast acetylators and whether mutations o
Publikováno v:
Clinical Science. 92:385-389
1. Mucositis is a common side-effect of chemotherapy which is difficult to assess except by invasive means such as upper gastrointestinal endoscopy. Differential absorption of mono- and di-saccharides, such as rhamnose and lactulose, is a non-invasiv
Autor:
R Herrmann, P Cannell, A Grigg, B. M. Dale, K Atkinson, Jeff Szer, David D.F. Ma, Timothy P. Hughes, J Ho, J E Norman, A P Schwarer, KM Taylor, R. E. Sage, Green Rm, C Arthur
Publikováno v:
British Journal of Haematology. 96:635-640
Mobilization of Philadelphia chromosome (Ph) negative blood progenitors was attempted in 23 newly diagnosed chronic myeloid leukaemia (CML) patients using a regimen of cyclophosphamide (CY) 5 g/m 2 and rHUG-CSF 1150 μg/m 2 daily. This regimen was we
Autor:
Dusan Kotasek, Michael C. Eaton, Alexander Dobrovic, R. E. Sage, Vivienne H. Pascoe, Jennifer E. Hardingham
Publikováno v:
Molecular Medicine. 1:789-794
Recurrent and metastatic carcinoma of the colorectum remains a major problem, with survival at 5 years post curative resection still only about 50%. Moreover, up to 30% of patients who present with early stage disease also relapse and die within 5 ye
Autor:
Alexander Dobrovic, R. E. Sage, A. Bolton, J X Mi, J. E. Norman, Jennifer E. Hardingham, B.M. Dale, L T Gooley, Dusan Kotasek
Publikováno v:
Journal of Clinical Oncology. 13:1073-1079
PURPOSE To evaluate the significance of molecular marker-positive cells in a cohort of non-Hodgkin's lymphoma (NHL) patients undergoing high-dose chemotherapy and autologous peripheral-blood stem-cell transplantation (PBSCT). PATIENTS AND METHODS Twe
Publikováno v:
Journal of Cardiovascular Pharmacology. 21:384-389
The effects of nitroglycerin (NTG) on platelet aggregation are controversial. Most in vitro investigations suggest that NTG suppresses platelet aggregation only at suprapharmacologic concentrations. We investigated various aspects of the antiaggregat
Publikováno v:
Leukemia & Lymphoma. 10:73-78
High dose hydroxyurea (HU) was used in a pilot study to assess its efficacy in mobilizing Philadelphia (Ph) chromosome negative progenitor cells in chronic myeloid leukaemia (CML). Five patients received 12 g/M2 oral HU in divided doses. Side effects