Zobrazeno 1 - 8
of 8
pro vyhledávání: '"R E, Mewshaw"'
Autor:
R. E. Mewshaw, M. Fox, Franklin F. Owings, Donald N. Kline, Conrad J. Kowalski, Neil Howard Baine, L.‐J. Ping, Ann Marie Tickner, T. M. Resnick
Publikováno v:
ChemInform. 26
Autor:
R. E. MEWSHAW, ET AL. ET AL.
Publikováno v:
ChemInform. 29
Autor:
R. E. MEWSHAW, et al. et al.
Publikováno v:
ChemInform. 29
Autor:
R. E. MEWSHAW, ET AL. ET AL.
Publikováno v:
ChemInform. 29
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 276(1)
Leumedins are small organic molecules with anti-inflammatory properties in vivo. We report here that leumedins inhibit the CD11b/CD18 alpha M beta 2 (Mac-1)-dependent adherence of neutrophils to serum proteins. The activation of neutrophils leading t
Autor:
G S, Hamilton, R E, Mewshaw, C M, Bryant, Y, Feng, G, Endemann, K S, Madden, J E, Janczak, J, Perumattam, L W, Stanton, X, Yang
Publikováno v:
Journal of medicinal chemistry. 38(10)
A series of fluoren-9-ylalkanoic and alkylbenzoic acids was prepared as simplified analogues of a previously reported series of antiinflammatory agents which act to inhibit neutrophil recruitment into inflamed tissue. The previous compounds ("leumedi
Autor:
R E, Mewshaw, L S, Silverman, R M, Mathew, C, Kaiser, R G, Sherrill, M, Cheng, C W, Tiffany, E W, Karbon, M A, Bailey, S A, Borosky
Publikováno v:
Journal of medicinal chemistry. 36(10)
A series of 5,6,7,8,9,10-hexahydro-7,10-iminocyclohept[b]indoles and 6,7,8,9,10,11-hexahydro-7,11-imino-5H-cyclooct[b]indoles was prepared. Structural modifications of the lead compound, 11-[4-(4-fluorobenzoyl)propyl]-5,6,7,8,9,10-hexahydro-7,10- imi
Publikováno v:
Drug design and delivery. 3(3)
Trans-tetrahydro-4-hydroxy-6-[1-aryl-7-naphthalenyl]-2H-pyran-2-ones of general structure 4 were prepared and tested for inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in vitro. In contrast to previously described biphenyl la