Zobrazeno 1 - 10
of 49
pro vyhledávání: '"R E, London"'
Publikováno v:
Allergy. 66(7)
Peanut allergy affects 1% of the population and causes the most fatal food-related anaphylactic reactions. The protein Ara h 2 is the most potent peanut allergen recognized by 80-90% of peanut allergic patients.The crystal structure of the major pean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25b93c35a284241360fae85186489d2b
https://pubmed.ncbi.nlm.nih.gov/21255036
https://pubmed.ncbi.nlm.nih.gov/21255036
Publikováno v:
Biochemical pharmacology. 60(7)
Acetylation of hemoglobin by aspirin and other compounds has been of interest for the development of agents useful for the treatment of sickle cell disease. In the present study, we have used 2D NMR methods in combination with [1-(13)C-acetyl]salicyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f8f2d2ca7a41848aabdf450cb1b3f4c
https://pubmed.ncbi.nlm.nih.gov/10974199
https://pubmed.ncbi.nlm.nih.gov/10974199
Publikováno v:
The Journal of biological chemistry. 275(41)
Reactivity of surface lysyl residues of proteins with a broad range of chemical agents has been proposed to be dependent on the catalytic microenvironment of the residue. We have investigated the acetylation of wild type ubiquitin and of the UbH68N m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16ab004342d50707bdf11f50b3f15302
https://pubmed.ncbi.nlm.nih.gov/10906321
https://pubmed.ncbi.nlm.nih.gov/10906321
Publikováno v:
Journal of biomolecular NMR. 15(1)
NMR experiments that transfer conformational information from the bound to the uncomplexed state via exchange have been utilized for many years. It is demonstrated here that inter-ligand NOEs ('ILOEs'), which exist in ternary complexes with enzymes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f784efe9c08ec05c51012db56765f4c3
https://pubmed.ncbi.nlm.nih.gov/10549135
https://pubmed.ncbi.nlm.nih.gov/10549135
Publikováno v:
The Journal of biological chemistry. 274(38)
The development of chemical modification agents that reduce the tendency of sickle hemoglobin (HbS) to aggregate represents an important chemotherapeutic goal. Methyl acetylphosphate (MAP) has been reported to bind to the 2,3-diphosphoglycerate (2,3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75aa87dcde479ebfd5e40acb60ad5e3f
https://pubmed.ncbi.nlm.nih.gov/10480863
https://pubmed.ncbi.nlm.nih.gov/10480863
Publikováno v:
Proteins. 36(1)
The theta subunit of DNA polymerase III, the main replicative polymerase of Escherichia coli, has been examined by circular dichroism and by NMR spectroscopy. The polymerase core consists of three subunits: alpha, epsilon, and theta, with alpha posse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9bfec68ce84c9ecd02361f2102a5dd6
https://pubmed.ncbi.nlm.nih.gov/10373010
https://pubmed.ncbi.nlm.nih.gov/10373010
Publikováno v:
The Journal of biological chemistry. 271(13)
Measurements of free calcium ion concentration in the sarcoplasmic reticulum ([Ca2+]SR) and an evaluation of its relationship to changes in cytosolic free calcium and energy state of the cell, as well as heterogeneity of the SR calcium pool, were per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d25686cd7ab08dfc79b4c5a026366d6
https://pubmed.ncbi.nlm.nih.gov/8631764
https://pubmed.ncbi.nlm.nih.gov/8631764
Autor:
R E London
Publikováno v:
Annual review of physiology. 53
Accurate and reproducible methods for the measurement of cytosolic free magnesium ion concentration, Mgj, are required in order to assess its physiologic role. This review covers two methods, in vivo nuclear magnetic resonance (NMR) and fluorescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a64a3e58cc3d056317e02003d3c41e
https://pubmed.ncbi.nlm.nih.gov/2042961
https://pubmed.ncbi.nlm.nih.gov/2042961
Publikováno v:
The American journal of physiology. 259(6 Pt 1)
Historically, increase in cell Na content during ischemic and hypoxic episodes were thought to result from impaired ATP production causing decreased Na(+)-K(+)-ATPase activity. Here we report the results of testing the alternate hypothesis that hypox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b3b274837d2676ae6b9362dda9fefb
https://pubmed.ncbi.nlm.nih.gov/2175547
https://pubmed.ncbi.nlm.nih.gov/2175547
Publikováno v:
Biochemical pharmacology. 40(1)
The use of NMR methods to study conformational and dynamic aspects of the proline residues in the nonapeptide bradykinin is reviewed. NMR analyses involve considerations of bistable equilibria which include the cis/trans conformational heterogeneity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0be3dc81d39ccfcf048cca64bb7d2af1
https://pubmed.ncbi.nlm.nih.gov/2372310
https://pubmed.ncbi.nlm.nih.gov/2372310