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Active transport of 3-O-methyl-glucose by the small intestine in chronically catheterized rats

Publikováno v: Journal of Clinical Investigation. 95:2799-2805

A method is described for determining the fraction of intestinal 3-O-methyl-glucose (3OMG) absorption that occurs by active transport in chronically catheterized rats without the influence of anesthesia or surgical bowel manipulation. That fraction w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e6481412f09adbd07c62fff8965149
https://doi.org/10.1172/jci117984

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The effect of surgical bowel manipulation and anesthesia on intestinal glucose absorption in rats

Autor: R E Kimura, Michael R. Uhing

Publikováno v: Journal of Clinical Investigation. 95:2790-2798

The effects of surgical bowel manipulation and anesthesia on intestinal glucose absorption were determined in chronically catheterized rats. Total and passive rates of glucose absorption were measured using 3-O-methyl-glucose (3OMG) and L-glucose, me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441967d6c5b9e18f4634ab336a0ef6d3
https://doi.org/10.1172/jci117983

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Indomethacin and pancreatic enzymes synergistically damage intestine of rats

Autor: R E, Kimura, V, Arango, J, Lloyd-Still

Publikováno v: Digestive diseases and sciences. 43(10)

The use of high-dose pancreatic enzymes by patients with cystic fibrosis was associated with the development of fibrosing colonopathy. Preliminary studies indicated that the infusion of high-dose pancreatic enzymes alone did not cause intestinal dama

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d41b61a4148291df608c8dac11d2a5d
https://pubmed.ncbi.nlm.nih.gov/9790472

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Neonatal intestinal metabolism

Autor: R E, Kimura

Publikováno v: Clinics in perinatology. 23(2)

In the presence of glutamine, glucose, and 3-hydroxybutyrate, glutamine is the preferred oxidative substrate in enterocytes of suckling and weaned rats. Our studies of changes in intestinal metabolism in the developing rat clearly indicate that the o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbf787807e9eacbf3eacb4e378a88f89
https://pubmed.ncbi.nlm.nih.gov/8780904

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Where does it hurt? An interdisciplinary approach to improving the quality of pain assessment and management in the neonatal intensive care unit

Autor: J B, Friedrichs, S, Young, D, Gallagher, C, Keller, R E, Kimura

Publikováno v: The Nursing clinics of North America. 30(1)

Identifying a premature infant's response to noxious stimuli and knowing when it is appropriate to intervene are major issues for the caregiver. After completing a pilot study, the staff of a 42-bed neonatal intensive care unit targeted improved pain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::513f399cd44df58871fe4ee0736dd44f
https://pubmed.ncbi.nlm.nih.gov/7885920

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Improved prediction of drug interactions using in vivo Ki

Autor: Stephen D. Hall, Y. C. Chen, Raymond E. Galinsky, V.A. Jiyamapa‐Sherna, R. E. Kimura, M. A. Hamman

Publikováno v: Clinical Pharmacology & Therapeutics. 75:P81

Drug-drug interactions are a leading cause of death in the U.S. CYP3A metabolism is the predominant pathway for drug metabolism. Itraconazole (ITZ) alters CYP3A activity resulting in clinically significant drug interactions. To date, in vitro studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::189cd5e7666879308de48734ff4f52bc
https://doi.org/10.1016/j.clpt.2003.11.308

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