Zobrazeno 1 - 10
of 26
pro vyhledávání: '"R E, Hurst"'
Autor:
R. E. Hurst
Publikováno v:
Science. 272:179d-183
Autor:
R E, Hurst
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 1(4)
Bexarotene (LGD-1069), from Ligand, was the first retinoid X receptor (RXR)-selective, antitumor retinoid to enter clinical trials. The company launched the drug for the treatment of cutaneous T-cell lymphoma (CTCL), as Targretin capsules, in the US
Publikováno v:
Cancer detection and prevention. 24(5)
The distribution of altered G-actin was investigated in prostatic cells obtained by fine needle aspiration (FNA) from 27 excised prostate glands obtained during radical prostatectomy. FNA, which was used to obtain single cells for image analysis, sam
Publikováno v:
Cancer. 89(2)
Additional molecular tissue biomarkers for prostate carcinoma are needed to stratify patients with clinically suspicious findings, such as an elevated prostate specific antigen (PSA) with a negative biopsy, according to risk.Prostate tissues from 43
Autor:
R E, Hurst, P, Waliszewski, M, Waliszewska, R B, Bonner, D M, Benbrook, A, Dar, G P, Hemstreet
Publikováno v:
Advances in experimental medicine and biology. 462
Carcinogenesis involves inactivation or subversion of the normal controls of proliferation, differentiation, and apoptosis. However, these controls are robust, redundant, and interlinked at the gene expression levels, regulation of mRNA lifetimes, tr
Publikováno v:
Journal of surgical oncology. 66(3)
Retinoids are metabolized in human intestinal epithelial cells to all-trans retinoic acid; however, it is unknown whether these cells express retinoid receptors, and whether sensitivity or resistance to the hormone is associated with a particular pat
Publikováno v:
International journal of cancer. 70(4)
Actin, a highly conserved protein comprising cell stress fibers and other cellular structures, is found in both the cytoplasm and nucleus of cells and responds to both epigenetic signals and altered gene expression occurring during tumorigenesis. We
Publikováno v:
Cytometry. 27(1)
We report on preliminary investigations of the use of an image analysis system to perform preliminary algorithmic classification of images of fluorochrome-labeled cells followed by capture of gray-level images of potentially abnormal cells for analys
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 5(12)
Bladder cancer detection, monitoring, and prevention represent major problems that could be addressed with sensitive and specific biomarkers. The antigen recognized by the DD23 antibody, previously developed against a tumor-related antigen, was parti
Autor:
G P, Hemstreet, J, Rao, R E, Hurst, R B, Bonner, P, Waliszewski, H B, Grossman, M, Liebert, B L, Bane
Publikováno v:
Journal of cellular biochemistry. Supplement. 25
Because tumorigenesis is an ongoing process, biomarkers can be used to identify individuals at risk for bladder cancer, and treatment of those at risk to prevent or slow further progression could be an effective means of cancer control given accurate