Zobrazeno 1 - 10
of 62
pro vyhledávání: '"R E, Humphreys"'
Publikováno v:
British Dental Journal. 209:601-606
Objective To explore the perceptions of first year foundation dentists (FD1s) regarding oral health education (OHE) and its role in general dental practice. Design Focus group discussions. Setting Postgraduate training venues and general dental pract
Autor:
Minzhen Xu, Y Li, S Wu, Yu Wang, Philippe Slos, Jennifer L Wright, R E Humphreys, Gilda G. Hillman, J. Li, Lu X, N L Kallinteris, J V Gulfo
Publikováno v:
Gene Therapy. 10:1512-1518
Tumor cells engineered by gene transduction to be MHC Class II+/Ii- are novel APCs capable of presenting endogenous tumor antigen epitopes to activate T helper cells. The MHC Class II+/Ii- tumor cell phenotype is created by transfecting genes for eit
Publikováno v:
Annals of the New York Academy of Sciences. 730:338-341
Publikováno v:
Scandinavian Journal of Immunology. 36:653-660
Summary The study of the immunobiology of FVIII inhibitors may lead to new therapies for this potentially severe complication of haemophilia A and to new principles for the use of therapeutic proteins. In order to characterize the idiotype-anti-idiot
Publikováno v:
The Journal of Immunology. 147:292-297
The activation of phosphoprotein tyrosine kinases was studied in the regulation of EBV activation in Akata cells after cross-linking membrane IgG with anti-IgG. Protein tyrosine phosphorylation was induced in Akata cells after stimulation with anti-I
Publikováno v:
The Journal of Immunology. 146:3877-3880
Class II MHC-associated invariant chain (Ii) might regulate binding of digested peptides to the Ag binding site (desetope) of class II MHC proteins by directly or allosterically blocking that site until cleavage and release of Ii from MHC alpha- and
Publikováno v:
The Journal of Immunology. 145:899-904
We tested the hypothesis that the recurrence of hydrophobic amino acids in a polypeptide at positions falling in an axial, hydrophobic strip if the sequence were coiled as an alpha helix, can lead to helical nucleation on a hydrophobic surface. The h
Publikováno v:
The Journal of Immunology. 144:4788-4793
Anti-IgG treatment activated latent EBV genomes in 50 to 70% of the cells of the Burkitt's lymphoma cell line Akata. The EBV-activating role of intracellular Ca2+, as potentiated by diacylglycerol (DAG) and suppressed by cAMP, was analyzed in the cel
Publikováno v:
Scandinavian journal of immunology. 54(1-2)
The discovery of the interactions of the 'Ii-Key' segment of the Ii protein with the major histocmpatibility complex (MHC) Class II allosteric site, which is adjacent to the antigenic peptide-binding site, creates therapeutic opportunities by regulat
Autor:
J K, Young, F, Marí, M, Xu, R E, Humphreys, N M, Clemente, J M, Stattel, D J, Nelson, J, Gambino, G E, Wright
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 50(2)
The 1H NMR-determined structure and dynamics of a synthetic, amphiphilic alpha-helical peptide, PH-1.0 (LYQELQKLTQTLK), and several homologs were compared in 50% trifluoroethanol-d2 (TFE-d2)/H20 and in sodium dodecyl-d25 sulfate (SDS-d25) micelles. T