Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R E, Hubbard"'
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Aims While the frailty index (FI) is a continuous variable, an FI score of 0.25 has construct and predictive validity to categorise community-dwelling older adults as frail or non-frail. Our study aimed to explore which FI categories (FI sco
Externí odkaz:
https://doaj.org/article/4decf87e9a75492ea758d136e1cff259
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Frailty is an indicator of physiological reserve in older people. In non-cancer settings, frailty indices are reliable predictors of adverse health outcomes. The aims of this study were to 1) derive and validate a frailty index (F
Externí odkaz:
https://doaj.org/article/bb0fb2ef4f5448eb83183f0750c7b7e4
Publikováno v:
Internal medicine journal. 44(10)
For frail older people, admission to hospital is an opportunity to review the indications for specific medications. This research investigates prescribing for 206 older people discharged into residential aged care facilities from 11 acute care hospit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d996bca6450b8555ab91871f9ac7482
https://pubmed.ncbi.nlm.nih.gov/25302723
https://pubmed.ncbi.nlm.nih.gov/25302723
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 27(5)
To compare the relative prognostic importance in older people of diagnosed diabetes, the number and severity of co-morbidities and frailty.Two thousand three hundred and five people agedor = 70 years comprised the clinical examination cohort of the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24710035aabfc47319989b5aa594a7e6
https://pubmed.ncbi.nlm.nih.gov/20536960
https://pubmed.ncbi.nlm.nih.gov/20536960
Publikováno v:
Biochemical Society transactions. 28(4)
We have determined the three-dimensional structures of both alpha- and beta-forms of the ligand-binding domain of the oestrogen receptor (ER) in complexes with a range of receptor agonists and antagonists. Here, we summarize how these structures prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dadc721f15c7b664b77a9b93b8251333
https://pubmed.ncbi.nlm.nih.gov/10961927
https://pubmed.ncbi.nlm.nih.gov/10961927
Publikováno v:
Proteins. 37(4)
Multiple-solvent crystal structure determination (MSCS) allows the position and orientation of bound solvent fragments to be identified by determining the structure of protein crystals soaked in organic solvents. We have extended this technique by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39666a15daf14af402b3cbed39ac309b
https://pubmed.ncbi.nlm.nih.gov/10651278
https://pubmed.ncbi.nlm.nih.gov/10651278
Publikováno v:
Journal of molecular biology. 285(2)
The crystal structure of the kinase domain of C-terminal Src kinase (CSK) has been determined by molecular replacement, co-complexed with the protein kinase inhibitor staurosporine (crystals belong to the space group P21212 with a=44.5 A, b=120.6 A,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33401c2c0093bc76b016a0c4e98072db
https://pubmed.ncbi.nlm.nih.gov/9878439
https://pubmed.ncbi.nlm.nih.gov/9878439
Autor:
P, Herzyk, R E, Hubbard
Publikováno v:
Journal of molecular biology. 281(4)
The electron density projection map of frog rhodopsin at 6 A resolution had been until recently the most direct evidence for the three-dimensional structure of a transmembrane domain of any G-protein-coupled receptor. Only three out of seven transmem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84a827029835a0fc5368216af5c42b79
https://pubmed.ncbi.nlm.nih.gov/9710543
https://pubmed.ncbi.nlm.nih.gov/9710543
Publikováno v:
Methods in enzymology. 287
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::704d61806beee99a5a5d9ae5994087e8
https://pubmed.ncbi.nlm.nih.gov/9330333
https://pubmed.ncbi.nlm.nih.gov/9330333
Publikováno v:
Insulin ISBN: 9783642741005
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a106bed32a32042df06abb7ec6d0679e
https://doi.org/10.1007/978-3-642-74098-5_2
https://doi.org/10.1007/978-3-642-74098-5_2
