Zobrazeno 1 - 10
of 108
pro vyhledávání: '"R E, Gay"'
Autor:
J. Charlesworth, J. Stankovich, P. Lewis, J. Byron, W. Stevens, J. Sahhar, S. Proudman, J. Roddy, P. Nash, K. Tymms, M. Brown, J. Zochling, A. Leask, S. Parapuram, X. Shiwen, C. Denton, D. Abraham, S. Liu, S. Vettori, M. Brock, N. Iwamoto, B. Maurer, A. Jungel, R. E. Gay, M. Calcagni, G. Valentini, J. H. Distler, S. Gay, O. Distler, S. Assassi, M. Mayes, X. Liu, B. Harper, E. Gonzalez, H. Draeger, X. Zhou, D. Khanna, D. Furst, F. Tan
Introduction. Understanding the genetic architecture of scleroderma (SSc) susceptibility is vital both in gene discovery and in determining the influence of previously identified susceptibility variants. It is particularly important in understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f3532eaa05d8f23dce6b3f3b5129a5
http://doc.rero.ch/record/302327/files/ker505.pdf
http://doc.rero.ch/record/302327/files/ker505.pdf
Publikováno v:
Zeitschrift fur Rheumatologie. 75(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9659b87cda9c5de466ef4028af1a82f0
https://pubmed.ncbi.nlm.nih.gov/27379741
https://pubmed.ncbi.nlm.nih.gov/27379741
Autor:
H. Maciejewska-Rodrigues, M. Al-Shamisi, H. Hemmatazad, C. Ospelt, M. C. Bouton, D. Jäger, A. P. Cope, P. Charles, D. Plant, J. H. W. Distler, R. E. Gay, B. A. Michel, A. Knuth, M. Neidhart, S. Gay, A. Jüngel
Publikováno v:
Arthritis & Rheumatism
Arthritis & Rheumatism; Vol 62
Arthritis & Rheumatism; Vol 62
OBJECTIVE: To search for novel autoantibodies in patients with rheumatoid arthritis (RA) in an effort to better understand the processes of joint destruction in this disease. METHODS: Using a modified SEREX technique and complementary DNA derived fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6015229ade22e00646b755251e84d95b
Autor:
A. Jungel, C. Ospelt, M. Lesch, M. Thiel, T. Sunyer, O. Schorr, B. A. Michel, R. E. Gay, C. Kolling, C. Flory, S. Gay, M. Neidhart
Publikováno v:
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases; Vol 69
Annals of the Rheumatic Diseases; Vol 69
Objective To evaluate the decrease of cartilage destruction by a novel orally active and specific matrix metalloproteinase 13 (MMP-13) inhibitor in three different animal models of rheumatoid arthritis (RA). Materials and methods The SCID mouse co-im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a584939ddbec8c875b49260227526801
Publikováno v:
Annals of the Rheumatic Diseases. 68:1334-1339
Background: Ankylosing spondylitis (AS) is a common, largely genetically determined, rheumatic disease that is characterised by spinal inflammation and new bone formation. However, the exact pathogenesis and pathology are still not clear. Objective:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45f76f3d258e98c26e425b474f02166
https://doi.org/10.1136/ard.2008.092494
https://doi.org/10.1136/ard.2008.092494
Publikováno v:
Rheumatology. 46:1063-1070
The TNF superfamily member LIGHT has a T-cell co-stimulatory role and has previously been associated with inflammation and autoimmunity. To investigate its role in rheumatoid arthritis (RA), a disease where activated T cells contribute in a prominent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93738501095ee5963fa991ffaaae66e
https://doi.org/10.1093/rheumatology/kem063
https://doi.org/10.1093/rheumatology/kem063
Autor:
L Senolt, M Grigorian, E Lukanidin, B Simmen, B A Michel, K Pavelka, R E Gay, S Gay, M Neidhart
Publikováno v:
Annals of the Rheumatic Diseases. 65:1645-1648
The metastasis‐associated protein S100A4 promotes the progression of cancer by regulating the remodelling of the extracellular matrix. The expression of S100A4 in vivo is shown and the functional role of S100A4 in the pathogenesis of osteoarthritis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5af61cdc24f9630124064f0171c1e6b
https://doi.org/10.1136/ard.2005.047704
https://doi.org/10.1136/ard.2005.047704
Publikováno v:
Annals of the Rheumatic Diseases. 64:419-424
Background: Galectin-3 is expressed in the synovial tissue of patients with rheumatoid arthritis (RA), particularly at sites of joint destruction. Objective: To explore the possibilities that galectin-3 is induced either by proinflammatory cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8c221f96e65d00d1146d7a4fdf17dd
https://doi.org/10.1136/ard.2004.023135
https://doi.org/10.1136/ard.2004.023135
Autor:
J Schedel, C A Seemayer, T Pap, M Neidhart, S Kuchen, B A Michel, R E Gay, U Müller-Ladner, S Gay, W Zacharias
Publikováno v:
Gene Therapy. 11:1040-1047
The present study was undertaken to examine whether ribozymes cleaving specifically cathepsin L (CL) mRNA are able to decrease the synthesis of CL protease in rheumatoid arthritis synovial fibroblasts (RA-SF) and thereby reduce the invasiveness into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10df379eaf9389af2489e0adde8d85c5
https://doi.org/10.1038/sj.gt.3302265
https://doi.org/10.1038/sj.gt.3302265