Zobrazeno 1 - 10
of 25
pro vyhledávání: '"R E, Diehl"'
Autor:
C A Omer, Patrick J. Casey, Bruno Giros, Fang L. Zhang, Jackson B. Gibbs, Nancy E. Kohl, R E Diehl
Publikováno v:
Journal of Biological Chemistry. 269:3175-3180
Protein geranylgeranyltransferase type-I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a carboxyl-terminal CAAX (C, cysteine; A, aliphatic amino acid; X, any amino acid) motif in which the "X" re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1322d5b63b646e0a7f15debdfa79fee9
https://doi.org/10.1016/s0021-9258(17)41845-x
https://doi.org/10.1016/s0021-9258(17)41845-x
Autor:
C A, Omer, Z, Chen, R E, Diehl, M W, Conner, H Y, Chen, M E, Trumbauer, S, Gopal-Truter, G, Seeburger, H, Bhimnathwala, M T, Abrams, J P, Davide, M S, Ellis, J B, Gibbs, I, Greenberg, K S, Koblan, A M, Kral, D, Liu, R B, Lobell, P J, Miller, S D, Mosser, T J, O'Neill, E, Rands, M D, Schaber, E T, Senderak, A, Oliff, N E, Kohl
Publikováno v:
Cancer research. 60(10)
For Ras oncoproteins to transform mammalian cells, they must be posttranslationally modified with a farnesyl group in a reaction catalyzed by the enzyme farnesyl:protein transferase (FPTase). Inhibitors of FPTase have therefore been developed as pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2912ec44ca2d1ecb77982ce053c4c10a
https://pubmed.ncbi.nlm.nih.gov/10825141
https://pubmed.ncbi.nlm.nih.gov/10825141
Publikováno v:
ACS Symposium Series ISBN: 9780841235465
Synthesis and Chemistry of Agrochemicals V
Synthesis and Chemistry of Agrochemicals V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d123d35c41cc28d44b68a929ffac97
https://doi.org/10.1021/bk-1998-0686.ch016
https://doi.org/10.1021/bk-1998-0686.ch016
Publikováno v:
Methods in enzymology. 250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e34c857da59c9822fbd9aabdcc8cfc12
https://pubmed.ncbi.nlm.nih.gov/7544423
https://pubmed.ncbi.nlm.nih.gov/7544423
Publikováno v:
The Journal of biological chemistry. 269(5)
Protein geranylgeranyltransferase type-I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a carboxyl-terminal CAAX (C, cysteine; A, aliphatic amino acid; X, any amino acid) motif in which the "X" re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::925b6fff9f08cd8159f69e401d377066
https://pubmed.ncbi.nlm.nih.gov/8106351
https://pubmed.ncbi.nlm.nih.gov/8106351
Autor:
S, Kargman, P, Rousseau, G K, Reid, C A, Rouzer, J A, Mancini, E, Rands, R A, Dixon, R E, Diehl, C, Léveillé, D, Nathaniel
Publikováno v:
Journal of lipid mediators. 7(1)
The U937 human promyelocytic cell line does not express 5-lipoxygenase, but does express 5-lipoxygenase-activating protein (FLAP). U937 cells do not synthesize leukotrienes after stimulation by calcium ionophore A23187. Dimethyl sulfoxide (DMSO) diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab90a3a479fe471dff2efce23b97cea7
https://pubmed.ncbi.nlm.nih.gov/8358023
https://pubmed.ncbi.nlm.nih.gov/8358023
Autor:
D. G. Kuhn, R. W. Addor, R. E. Diehl, J. A. Furch, V. M. Kamhi, K. E. Henegar, K. A. Kremer, G. T. Lowen, B. C. Black, T. P. Miller, M. F. Treacy
Publikováno v:
ACS Symposium Series ISBN: 9780841226388
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f23023b7e4973eedd0efd0b697be4ba9
https://doi.org/10.1021/bk-1993-0524.ch015
https://doi.org/10.1021/bk-1993-0524.ch015
Autor:
R. W. Addor, T. J. Babcock, B. C. Black, D. G. Brown, R. E. Diehl, J. A. Furch, V. Kameswaran, V. M. Kamhi, K. A. Kremer, D. G. Kuhn, J. B. Lovell, G. T. Lowen, T. P. Miller, R. M. Peevey, J. K. Siddens, M. F. Treacy, S. H. Trotto, D. P. Wright
Publikováno v:
Synthesis and Chemistry of Agrochemicals III ISBN: 9780841224735
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d33188d618ef9235962e9402aff2c10
https://doi.org/10.1021/bk-1992-0504.ch025
https://doi.org/10.1021/bk-1992-0504.ch025
Autor:
N E, Kohl, R E, Diehl, M D, Schaber, E, Rands, D D, Soderman, B, He, S L, Moores, D L, Pompliano, S, Ferro-Novick, S, Powers
Publikováno v:
The Journal of biological chemistry. 266(28)
Farnesyl-protein transferase (FTase) purified from rat or bovine brain is an alpha/beta heterodimer, comprised of subunits having relative molecular masses of approximately 47 (alpha) and 45 kDa (beta). In the yeast Saccharomyces cerevisiae, two unli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5004aea0d39c9055e985825403b5c4c1
https://pubmed.ncbi.nlm.nih.gov/1918005
https://pubmed.ncbi.nlm.nih.gov/1918005
Publikováno v:
The Journal of biological chemistry. 266(13)
The human gene for the recently identified 5-lipoxy-genase-activating protein (FLAP) has been cloned. The gene was isolated from two different genomic libraries and is contained within four overlapping bacteriophage clones. The gene spans greater tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ea62f08b24cbccf923aa1d67c9f3500
https://pubmed.ncbi.nlm.nih.gov/1673682
https://pubmed.ncbi.nlm.nih.gov/1673682