Zobrazeno 1 - 10
of 288
pro vyhledávání: '"R DeLeo"'
Autor:
Natalia Malachowa, Daniel E. Sturdevant, Adeline R. Porter, Grant Martin, Craig Martens, Vinod Nair, Bryan Hansen, Stacy Ricklefs, Stephen G. Jenkins, Liang Chen, Barry N. Kreiswirth, Frank R. DeLeo
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Staphylococcus aureus is a leading cause of healthcare-associated infections globally. Vancomycin-resistant S. aureus (VRSA), those with high-level resistance [minimum inhibitory concentration (MIC) of 16–32 µg/mL vancomycin], are uncommo
Externí odkaz:
https://doaj.org/article/8cbaf093e0154a78bdd7d09c1332d7ee
Autor:
Frank R. DeLeo, Adeline R. Porter, Scott D. Kobayashi, Brett Freedman, Mingju Hao, Jianping Jiang, Yi-Tsung Lin, Barry N. Kreiswirth, Liang Chen
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Klebsiella pneumoniae is an important cause of healthcare-associated infections worldwide. This opportunistic pathogen, known as classical K. pneumoniae (cKp), typically causes infections in individuals with comorbidities. cKp is often multi
Externí odkaz:
https://doaj.org/article/0c5715eb42e348358c2c4a49984d9718
Innate Host Defense against Klebsiella pneumoniae and the Outlook for Development of Immunotherapies
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2021)
Klebsiella pneumoniae (K. pneumoniae) is a Gram-negative commensal bacterium and opportunistic pathogen. In healthy individuals, the innate immune system is adept at protecting against K. pneumoniae infection. Notably, the serum complement system and
Externí odkaz:
https://doaj.org/article/19dc743ae6d5490abe522b9b9065d2a0
Autor:
Clement Opoku-Temeng, Brett Freedman, Adeline R. Porter, Scott D. Kobayashi, Liang Chen, Barry N. Kreiswirth, Frank R. DeLeo
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Carbapenem-resistant Klebsiella pneumoniae isolates classified as multilocus sequence type 258 (ST258) are a problem in health care settings in many countries globally. ST258 isolates are resistant to multiple classes of antibiotics and can
Externí odkaz:
https://doaj.org/article/e6821ac3fdb142899e410a6c0850d165
Autor:
Natalia Malachowa, Will McGuinness, Scott D. Kobayashi, Adeline R. Porter, Carl Shaia, Jamie Lovaglio, Brian Smith, Viktoria Rungelrath, Greg Saturday, Dana P. Scott, Fabiana Falugi, Dominique Missiakas, Olaf Schneewind, Frank R. DeLeo
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Staphylococcus aureus remains a leading cause of skin and soft tissue infections (SSTIs) globally. In the United States, many of these infections are caused by isolates classified as USA300. Our understanding of the success of USA300 as a hu
Externí odkaz:
https://doaj.org/article/3bd61d6df61c4ce5a25836c22438198e
Autor:
Viktoria Rungelrath, Adeline R. Porter, Natalia Malachowa, Brett A. Freedman, Jacqueline M. Leung, Jovanka M. Voyich, Michael Otto, Scott D. Kobayashi, Frank R. DeLeo
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Staphylococcus aureus is an important human pathogen that can cause a variety of diseases ranging from mild superficial skin infections to life-threatening conditions like necrotizing pneumonia, endocarditis, and septicemia. Polymorphonuclea
Externí odkaz:
https://doaj.org/article/37e9e44db31b477bbb44ffe3b731b0c6
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1360-1366 (2019)
Carbapenem-resistant (CR) Klebsiella pneumoniae has emerged as an urgent public health threat in many industrialized countries worldwide, including the United States. Infections caused by CR K. pneumoniae are difficult to treat because these organism
Externí odkaz:
https://doaj.org/article/9197a0378b9f43dab74174712024c30e
Autor:
Shayla Hesse, Natalia Malachowa, Adeline R. Porter, Brett Freedman, Scott D. Kobayashi, Donald J. Gardner, Dana P. Scott, Sankar Adhya, Frank R. DeLeo
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Infections caused by multidrug-resistant K. pneumoniae
Externí odkaz:
https://doaj.org/article/aebcf3ef228d47a7adcfddd0af92f87a
Autor:
Priyanka Kachroo, Jesus M. Eraso, Randall J. Olsen, Luchang Zhu, Samantha L. Kubiak, Layne Pruitt, Prasanti Yerramilli, Concepcion C. Cantu, Matthew Ojeda Saavedra, Johan Pensar, Jukka Corander, Leslie Jenkins, Lillian Kao, Alejandro Granillo, Adeline R. Porter, Frank R. DeLeo, James M. Musser
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT A fundamental goal of contemporary biomedical research is to understand the molecular basis of disease pathogenesis and exploit this information to develop targeted and more-effective therapies. Necrotizing myositis caused by the bacterial p
Externí odkaz:
https://doaj.org/article/b1f2ba781c34426ea2c3cb8707edf5d5
Autor:
Jesus M Eraso, Priyanka Kachroo, Randall J Olsen, Stephen B Beres, Luchang Zhu, Traci Badu, Sydney Shannon, Concepcion C Cantu, Matthew Ojeda Saavedra, Samantha L Kubiak, Adeline R Porter, Frank R DeLeo, James M Musser
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229064 (2020)
Streptococcus pyogenes is a strict human pathogen responsible for more than 700 million infections annually worldwide. Strains of serotype M28 S. pyogenes are typically among the five more abundant types causing invasive infections and pharyngitis in
Externí odkaz:
https://doaj.org/article/0b9f20ab49cd46bfb9afa9d9f90b1c26