Výsledky vyhledávání - "R De Waal-Malefyt"

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Selective development of a strong Th2 cytokine profile in high-risk children who develop atopy: risk factors and regulatory role of IFN-γ, IL-4 and IL-10

Autor: Huub F. J. Savelkoul, M.R.M. Baert, Herman J. Neijens, R. De Waal Malefyt, M.P. Laan, V H J van der Velden

Publikováno v: Clinical & Experimental Allergy. 31:997-1006

Background The immunological processes in early life and their relation to allergic sensitization leading to a Th2 cytokine profile are still not well understood. Objective To analyse the environmental and genetic risk factors and immunological respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82fc4b223e435eb2a6e0f65f1349f7ae
https://doi.org/10.1046/j.1365-2222.2001.01176.x

Zobrazit plný text záznamu

T cell activation and anti-tumor efficacy of anti-Lag3 mAbs are independent of Lag-3–MHC Class II blocking capacity

Autor: Edward Hsieh, Saso Cemerski, S. Zhao, Wendy M. Blumenschein, R. Shukla, R. De Waal Malefyt, Long Cui, Melissa Chenard, Brian B. Haines, Jason Laskey, Tatyana Churakova, Laurence Fayadat-Dilman, Maribel Beaumont

Publikováno v: European Journal of Cancer. 69:S98

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b97953e806321eb752b89048536a01a
https://doi.org/10.1016/s0959-8049(16)32891-x

Zobrazit plný text záznamu

Multiple sclerosis: comparison of the human T-cell response to S100 beta and myelin basic protein reveals parallels to rat experimental autoimmune panencephalitis

Autor: Stefano Sotgiu, R. de Waal Malefyt, Christopher Linington, Reinhard Hohlfeld, Stephan Schmidt, Frauke Zipp, Hartmut Wekerle

Publikováno v: Brain. 120:1437-1445

The adoptive transfer of autoreactive S100 beta-specific T cells induces experimental autoimmune panencephalomyelitis and uveoretinitis in the Lewis rat, mimicking the distribution of lesions seen in a subset of patients with multiple sclerosis. We s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d47cbd655d593a3c6d3529f88fba1f
https://doi.org/10.1093/brain/120.8.1437

Zobrazit plný text záznamu

Expression cloning and characterization of a human IL-10 receptor

Autor: Y Liu, S H Wei, A S Ho, R de Waal Malefyt, K W Moore

Publikováno v: The Journal of Immunology. 152:1821-1829

cDNA clones encoding a human IL-10R (hIL-10R) from a Burkitt lymphoma cell line, BJAB, express a 90 to 110 kDa polypeptide in COS7 cells that binds hIL-10 specifically. The predicted amino acid sequence of hIL-10R is 60% identical and 73% similar to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::597441ec41bb459dfdf1d9b452200a43
https://doi.org/10.4049/jimmunol.152.4.1821

Zobrazit plný text záznamu

High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells

Autor: R de Waal Malefyt, Pier-Angelo Tovo, Maria Grazia Roncarolo, Robertson Parkman, Rosa Bacchetta, M. Bigler, Jean Louis Touraine, John S. Abrams, J E de Vries

Publikováno v: The Journal of Experimental Medicine
Scopus-Elsevier

Transplantation of HLA mismatched hematopoietic stem cells in patients with severe combined immunodeficiency (SCID) can result in a selective engraftment of T cells of donor origin with complete immunologic reconstitution and in vivo tolerance. The l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5e611387c1221fab652441e87305c5
http://europepmc.org/articles/PMC2191349

Zobrazit plný text záznamu

Interleukin 10 inhibits transforming growth factor-beta (TGF-beta) synthesis required for osteogenic commitment of mouse bone marrow cells

Autor: U. Van Gorp, J R Dasch, P. Van Vlasselaer, B. Borremans, R De Waal-Malefyt

Publikováno v: The Journal of Cell Biology

Interleukin 10 (IL-10) suppressed TGF-beta synthesis in mouse bone marrow cultures. Coincidingly, IL-10 down-regulated the production of bone proteins including alkaline phosphatase (ALP), collagen and osteocalcin, and the formation of mineralized ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eafc798fc0e83f625a631585071cc662
http://europepmc.org/articles/PMC2119922

Zobrazit plný text záznamu

An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors

Autor: S M Zurawski, Felix Vega, J. Punnonen, Benjamin G. Cocks, R de Waal Malefyt, G Zurawski, Gregorio Aversa, J E de Vries

Publikováno v: The Journal of Experimental Medicine

Interleukin 4 (IL-4) and IL-13 share many biological functions. Both cytokines promote growth of activated human B cells and induce naive human surface immunoglobulin D+ (sIgD+) B cells to produce IgG4 and IgE. Here we show that a mutant form of huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f267fa3d2b82777e812c2e4652f1e3
https://doi.org/10.1084/jem.178.6.2213

Zobrazit plný text záznamu

Interleukin-10 inhibits the osteogenic activity of mouse bone marrow

Autor: P. Van Vlasselaer, B. Borremans, R de Waal Malefyt, U. Van Gorp, R. Van Den Heuvel

Publikováno v: Scopus-Elsevier

Murine bone marrow cells synthesize bone proteins, including alkaline phosphatase (ALP), collagen type I, and osteocalcin, and form a mineralized extracellular matrix when cultured in the presence of beta- glycerophosphate and vitamin C. Interleukin-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61864675dd14937033dc0259972223c7
https://doi.org/10.1182/blood.v82.8.2361.bloodjournal8282361

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání