Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R D McDermott-Lancaster"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 41:326-330
Groups of nude mice, with both hind footpads infected with 10(8) Mycobacterium leprae organisms, were treated with 4-week courses of different drug combinations. The effect treatment on each group was evaluated by subinoculating footpad homogenates f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45697045f6faf8998fbd7bf89f770391
https://doi.org/10.1128/aac.41.2.326
https://doi.org/10.1128/aac.41.2.326
Activity of sparfloxacin against Mycobacterium leprae measured by the proportional bactericidal test
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 61(4)
The activity of 25 mg/kg and 50 mg/kg sparfloxacin was measured against Mycobacterium leprae in normal (immunocompetent) mouse foot pads by the proportional bactericidal test. This was compared with the action of 25, 50, and 150 mg/kg ofloxacin by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ffe226960c855c4441023831be421058
https://pubmed.ncbi.nlm.nih.gov/8151193
https://pubmed.ncbi.nlm.nih.gov/8151193
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 60(3)
The bactericidal effect of a new quinolone, ofloxacin (OFLO), was determined on an established Mycobacterium leprae infection in nude mice. Various drug regimens, including combinations of drugs, were examined for different treatment periods. OFLO an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d041a4028072d59c9df7463d478ee68
https://pubmed.ncbi.nlm.nih.gov/1474279
https://pubmed.ncbi.nlm.nih.gov/1474279
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 58(4)
The possibility of synergy between immunotherapy with recombinant interferon-gamma (IFN-gamma) and chemotherapy with rifampin (RMP) and dapsone (DDS) against Mycobacterium leprae was examined in nude mice. IFN-gamma alone failed to show any effect on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1827329aa4a90780af7af10c0fd94c70
https://pubmed.ncbi.nlm.nih.gov/2126271
https://pubmed.ncbi.nlm.nih.gov/2126271
Publikováno v:
Journal of Medical Microbiology. 25:13-15
Summary A strain of Mycobacterium leprae resistant to rifampicin (RMP) failed to infect normal mice when injected into the foot pads (FP) at a dose of 10 or 100 bacilli/FP, although it could be maintained by serial passage in mice by the use of inocu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92956bd324b652c1e70704e34dad840f
https://doi.org/10.1099/00222615-25-1-13
https://doi.org/10.1099/00222615-25-1-13
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09192ffd7375ae6b252dd285ed0ed5bc
https://pubmed.ncbi.nlm.nih.gov/3437169
https://pubmed.ncbi.nlm.nih.gov/3437169
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 55
Two aspects of the immune deficiency of nude mice make these animals particularly useful tools for leprosy research. Nude mice are capable of supporting multiplication of M. leprae to levels approaching 10(10) per g in peripheral body tissues. In add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15f04be4819f64dc913372d728ed64bf
https://pubmed.ncbi.nlm.nih.gov/3325583
https://pubmed.ncbi.nlm.nih.gov/3325583