Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R D Laurie"'
Publikováno v:
Drug and chemical toxicology. 13(1)
Subacute (10-day) and subchronic (90-day) toxicity studies of ethylene glycol (EG) were conducted in male and female Sprague-Dawley rats to provide the U.S. Environmental Protection Agency's (EPA) Office of Drinking Water with toxicity data for final
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53df7a011a13b250d37b2d76dba5b70b
https://pubmed.ncbi.nlm.nih.gov/2379473
https://pubmed.ncbi.nlm.nih.gov/2379473
Publikováno v:
Environmental Health Perspectives
The responsiveness of SENCAR mouse skin to 20 different chemicals with known carcinogenic properties was assessed in initiation/promotion experiments. The purpose of these experiments was to evaluate the extent of false negative responses in mouse sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8611c86f51d44fceed1395dcc1bef009
https://doi.org/10.1289/ehp.866811
https://doi.org/10.1289/ehp.866811
Publikováno v:
Fundamental and Applied Toxicology. 5:1065-1074
The present study was undertaken to determine if chlorinated and brominated acetonitriles formed during the chlorination of drinking water possess mutagenic and/or carcinogenic properties. Chloroacetonitrile (CAN), dichloroacetonitrile (DCAN), trichl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::019ec7d78af0fa623b183528e4d5d55e
https://doi.org/10.1016/0272-0590(85)90142-3
https://doi.org/10.1016/0272-0590(85)90142-3
Publikováno v:
Journal of Toxicology and Environmental Health. 15:315-322
Chlorine dioxide (ClO2), an alternative to chlorine for drinking water disinfection, has been implicated as a potential antithyroid agent (Bercz et al., 1982). Because antithyroid compounds are known to alter neurobehavioral development, the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee06af7cbeff2739870d0347cd57551
https://doi.org/10.1080/15287398509530657
https://doi.org/10.1080/15287398509530657
Publikováno v:
Toxicological Sciences. 5:1065-1074
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2b7bafea8df377ac36e1fa8822fb66e
https://doi.org/10.1093/toxsci/5.6part1.1065
https://doi.org/10.1093/toxsci/5.6part1.1065
Publikováno v:
Drug and Chemical Toxicology. 6:563-578
The renal and hepatotoxicities of five selected halomethanes, which are drinking water contaminants, were evaluated following a 14-day exposure. Bromodichloromethane, bromoform, chloroform, dibromochloromethane and methylene chloride were administere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef35abecc2e924f5b54ed9ad8882f10c
https://doi.org/10.3109/01480548309017810
https://doi.org/10.3109/01480548309017810
Publikováno v:
Environmental Health Perspectives
A large number and variety of compounds are formed in the process of chlorinating drinking water. The classes of compounds formed include trihalomethanes, haloacetic acids, haloacetonitriles, halophenols, and halopropanones. Many of the compounds hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e788c4da7cfdacf376bcf25fa93c79
http://europepmc.org/articles/PMC1474302
http://europepmc.org/articles/PMC1474302
Publikováno v:
Cancer research. 44(1)
Acrylamide structurally resembles vinyl carbamate, a proposed proximate carcinogenic form of ethyl carbamate. To test the hypothesis that acrylamide should possess carcinogenic properties, it was tested in the Salmonella-microsome assay for point mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cc49115d8b4f0c93baac51749e18f71
https://pubmed.ncbi.nlm.nih.gov/6360343
https://pubmed.ncbi.nlm.nih.gov/6360343
Publikováno v:
Journal of toxicology and environmental health. 15(2)
A subchronic 90-d study was conducted with chlorinated and nonchlorinated humic acids using male Sprague-Dawley rats. Body weight gain, terminal organ and body weights, food and fluid consumption, clinical chemistries, hematological parameters, and u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e9d703a55f0f96374898fc08d831c0
https://pubmed.ncbi.nlm.nih.gov/3159908
https://pubmed.ncbi.nlm.nih.gov/3159908
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 7(2)
This investigation was conducted to evaluate the effect of gavage vehicles on altering the severity of the subchronic hepatotoxicity of carbon tetrachloride (CCl4). Male and female CD-1 mice were gavaged with 0, 1.2, 12, and 120 mg/kg CCl4 in either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d65f97259478679dd108ffb5a986a412
https://pubmed.ncbi.nlm.nih.gov/3758537
https://pubmed.ncbi.nlm.nih.gov/3758537