Zobrazeno 1 - 10
of 16
pro vyhledávání: '"R D, Vale"'
Publikováno v:
Traffic (Copenhagen, Denmark). 1(1)
Cytoplasmic dynein, a large minus-end-directed microtubule motor, performs multiple functions during the cell cycle. In interphase, dynein moves membrane organelles, while in mitosis it moves chromosomes and helps to form the mitotic spindle. The cel
Publikováno v:
Cell. 103(4)
Autor:
M, Tomishige, R D, Vale
Publikováno v:
The Journal of Cell Biology
Conventional kinesin, a dimeric molecular motor, uses ATP-dependent conformational changes to move unidirectionally along a row of tubulin subunits on a microtubule. Two models have been advanced for the major structural change underlying kinesin mot
Autor:
R D, Vale
Publikováno v:
The Journal of Cell Biology
Autor:
B, Govindan, R D, Vale
Publikováno v:
Cell motility and the cytoskeleton. 45(1)
The dynamic properties of microtubules (MTs) are important for a wide variety of cellular processes, including cell division and morphogenesis. MT assembly and disassembly in vivo are regulated by cellular factors that influence specific parameters o
Autor:
R D, Vale
Publikováno v:
Trends in cell biology. 9(12)
In a universe that is dominated by increasing entropy, living organisms are a curious anomaly. The organization that distinguishes living organisms from their inanimate surroundings relies upon their ability to execute vectorial processes, such as di
Publikováno v:
Journal of muscle research and cell motility. 19(8)
Recent studies have shown surprising structural and functional similarities between the motor domains of kinesin and myosin. Common features have also been described for motor proteins and G proteins. Despite these similarities, the evolutionary rela
Autor:
D W, Pierce, R D, Vale
Publikováno v:
Methods in cell biology. 58
Autor:
D W, Pierce, R D, Vale
Publikováno v:
Methods in enzymology. 298
Publikováno v:
Cell motility and the cytoskeleton. 40(3)
The transport of vesicular organelles along microtubules has been well documented in a variety of systems, but the molecular mechanisms underlying this process are not well understood. We have developed a method for preparing extracts from Dictyostel