Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R D, Raffaniello"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 269:G400-G407
Rab3 proteins are low molecular weight guanine nucleotide-binding proteins that belong to the Ras superfamily and are believed to play a role in the final steps of exocytosis. To examine potential interactions of these proteins with signaling pathway
Actions of Helodermatidae venom peptides and mammalian glucagon-like peptides on gastric chief cells
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 265:G118-G125
The actions of peptides (helospectin I, helodermin, exendin-3, exendin-4) that have been isolated from the venoms of Helodermatidae lizards were examined using dispersed chief cells from guinea pig stomach. These actions were compared with those of m
Autor:
M. Steenport, M. Uezu, E. W. Straus, R. D. Raffaniello, R. Gupta, Y. Mustafa, H. Eom, R. Villanueva, J. Schneller
Publikováno v:
Oncology reports. 18(1)
Gastric carcinogenesis is a multistep process progressing from chronic gastritis, through glandular atrophy (GA), intestinal metaplasia (IM) and dysplasia. We have previously demonstrated that minority patients at New York City hospitals are infected
Publikováno v:
Digestive diseases and sciences. 51(10)
Gastric carcinogenesis is a multistep process progressing from chronic gastritis, through glandular atrophy (GA), intestinal metaplasia (IM) and dysplasia. Infection of the stomach with H. pylori increases the risk of developing gastric cancer. Few s
Autor:
E W, Straus, H, Patel, J, Chang, R M, Gupta, V, Sottile, J, Scirica, G, Tarabay, S, Iyer, S, Samuel, R D, Raffaniello
Publikováno v:
Digestive diseases and sciences. 47(7)
Kings County Hospital (KCH), and St. John's Episcopal Hospital (SJH) are inner-city hospitals in New York City serving predominantly minority populations. Staten Island University Hospital (SIUH) serves a predominantly middle-class Caucasian populati
Publikováno v:
Journal of cellular physiology. 185(3)
Rab proteins are geranylgeranylated on their carboxyl terminal cysteine motifs by geranylgeranyltransferase II (GGTase). Rab escort protein (REP) is required to present Rab proteins to GGTase. REP may remain bound to newly isoprenylated Rab proteins
Autor:
R D, Raffaniello, J P, Raufman
Publikováno v:
Journal of cellular biochemistry. 72(4)
Rab3D, a low-molecular-weight GTP-binding protein believed to be involved with regulated exocytosis, is associated with secretory granules in gastric chief cells. Although Rab3D is predominantly membrane associated, a significant fraction is cytosoli
Publikováno v:
Journal of cellular biochemistry. 64(3)
In gastric chief cells, agents that activate protein kinase C (PKC) stimulate pepsinogen secretion and phosphorylation of an acidic 72-kDa protein. The isoelectric point and molecular mass of this protein are similar to those for a common PKC substra
Publikováno v:
The Journal of biological chemistry. 271(33)
In cholera toxin-treated gastric chief cells, incubation with a cholinergic agonist (carbamylcholine), a regulatory peptide (cholecystokinin), or a calcium ionophore (A23187) causes a dose- and time-dependent potentiation of cAMP levels. Because this
Autor:
R D, Raffaniello, J P, Raufman
Publikováno v:
The Journal of biological chemistry. 268(12)
Nonhydrolyzable guanine nucleotide analogues were used to evaluate the role of guanine nucleotide binding (G) proteins in regulating pepsinogen secretion from streptolysin O-permeabilized chief cells from guinea pig stomach. In the presence of 100 nM