Zobrazeno 1 - 10
of 24
pro vyhledávání: '"R D, MACKENZIE"'
Publikováno v:
Journal of International Medical Research. 4:375-381
Since no practical animal model is available for the evaluation of compounds in vivo, we have developed an in vitro model for determining the effect of compounds on the rate of sickling of erythrocytes in whole blood taken from patients with sickle c
Autor:
R. D. Mackenzie, G. M. Findlay
Publikováno v:
The Journal of Pathology and Bacteriology. 43:205-208
Publikováno v:
The Journal of Pathology and Bacteriology. 45:589-596
Autor:
R. D. Mackenzie
Publikováno v:
The Journal of Pathology and Bacteriology. 37:75-79
Autor:
R. D. Mackenzie
Publikováno v:
The Journal of Pathology and Bacteriology. 40:65-73
Autor:
R. S. Marshall, R. D. Mackenzie
Publikováno v:
The Journal of Pathology and Bacteriology. 35:175-182
Publikováno v:
Journal of medicinal chemistry. 19(10)
(E)-4-[4-(Methylthio)phenyl]-1-(2-piperidinyl)-3-buten-2-one hydrochloride (44, RMI 14 133A) was found to inhibit ADP-induced aggregation of blood platelets. It was selected from a large series of (2-piperidinyl)- and (2-pyrrolidinyl)ethanones synthe
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 162(1)
SummaryRMI 11,071 A, one of a series of lactamimides, was found to inhibit the sick-ling rate in an in vitro system. This inhibition was not total or permanent; the sickling rate increased after 30 min at low O2 tension and the number of sickled cell
Publikováno v:
Chemischer Informationsdienst. 7
Autor:
G. L. Schatzman, R. D. Mackenzie
Publikováno v:
Scandinavian journal of haematology. 15(1)
Tilorone hydrochloride was tested in vitro for inhibition of platelet aggregation in the ADP, collagen, and epinephrine-induced platelet aggregation systems. Tilorone did not significantly inhibit the first phase of platelet aggregation induced by AD