Zobrazeno 1 - 10
of 183
pro vyhledávání: '"R D, Lund"'
Transplantation of human central nervous system stem cells - neuroprotection in retinal degeneration
Autor:
R. D. Lund, Benjamin Cottam, Trevor J. McGill, Chunyu Tian, Stephen L. Huhn, Shaomei Wang, S.V. Girman, Alexandra Capela, Bin Lu
Publikováno v:
European Journal of Neuroscience. 35:468-477
Stem cells derived from the human brain and grown as neurospheres (HuCNS-SC) have been shown to be effective in treating central neurodegenerative conditions in a variety of animal models. Human safety data in neurodegenerative disorders are currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6082a25b6f62d45ae5cba2c214215bf1
https://doi.org/10.1111/j.1460-9568.2011.07970.x
https://doi.org/10.1111/j.1460-9568.2011.07970.x
Autor:
R. D. Lund, S.V. Girman
Publikováno v:
Journal of Neurophysiology. 98:161-177
The uppermost layer (stratum griseum superficiale, SGS) of the superior colliculus (SC) provides an important gateway from the retina to the visual extrastriate and visuomotor systems. The majority of attention has been given to the role of this “v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13535a6223d8b23f389034638eb34340
https://doi.org/10.1152/jn.00059.2007
https://doi.org/10.1152/jn.00059.2007
Autor:
R. D. Lund, S.V. Girman
Publikováno v:
Journal of neurophysiology. 104(6)
In the primary visual cortex (V1), it has been shown that the neuronal response elicited by a grating patch in the receptive field (RF) center can be suppressed or facilitated by an annular grating presented in the RF surround area; the effect depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281f0b818488dcddeffb7d9d7e2a9fa7
https://pubmed.ncbi.nlm.nih.gov/20861426
https://pubmed.ncbi.nlm.nih.gov/20861426
Publikováno v:
Experimental eye research. 91(3)
Visual impairment associated with photoreceptor degeneration is a largely untreatable condition affecting millions of people worldwide. Cellular therapies offer an attractive alternative for the treatment of retinal degeneration. Human adult bone mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9134c72359510a6629e998baf676a4c
https://pubmed.ncbi.nlm.nih.gov/20603115
https://pubmed.ncbi.nlm.nih.gov/20603115
Autor:
Bin Lu, Trevor J. McFarland, Markus Grompe, Jie Duan, Grazyna Adamus, Sergei Girman, R. D. Lund, Qing Shuo Zhang, Binoy Appukuttan, Shaomei Wang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 2, p e9200 (2010)
PLoS ONE, Vol 5, Iss 2, p e9200 (2010)
BACKGROUND: Retinitis pigmentosa (RP) is characterized by progressive night blindness, visual field loss, altered vascular permeability and loss of central vision. Currently there is no effective treatment available except gene replacement therapy ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde9f1a2fcb7fe182b62a3610064c349
https://pubmed.ncbi.nlm.nih.gov/20169166
https://pubmed.ncbi.nlm.nih.gov/20169166
Autor:
Robert Lanza, R. D. Lund, Christopher Malcuit, Bin Lu, Linda Lemieux, S.V. Girman, Shaomei Wang, Peter J. Francis
Publikováno v:
Stem cells (Dayton, Ohio). 27(9)
Assessments of safety and efficacy are crucial before human ESC (hESC) therapies can move into the clinic. Two important early potential hESC applications are the use of retinal pigment epithelium (RPE) for the treatment of age-related macular degene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad9984d04ccb9310809f8c0a2fefd76
https://pubmed.ncbi.nlm.nih.gov/19521979
https://pubmed.ncbi.nlm.nih.gov/19521979
Autor:
R. D. Lund, Shaomei Wang
Publikováno v:
Ophthalmology Research ISBN: 9781588296207
The first studies showing the potential of retinal cell transplantation to alleviate the progress of blindness in an animal model of retinal disease, the Royal College of Surgeons (RCS) rat, were focused on the fact that in this animal there was a kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afc52e3461979de28c93f9674cde7980
https://doi.org/10.1007/978-1-59745-186-4_17
https://doi.org/10.1007/978-1-59745-186-4_17
Autor:
A C E, Symonds, C E, King, C A, Bartlett, Y, Sauvé, R D, Lund, L D, Beazley, S A, Dunlop, J, Rodger
Publikováno v:
The European journal of neuroscience. 25(3)
During development, gradients of EphA receptors (nasal(low)-temporal(high)) and their ligands ephrin-As (rostral(low)-caudal(high)) are involved in establishing topography between retinal ganglion cells (RGCs) and the superior colliculus (SC). EphA5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9e237343ed3a0ed010e3706f6f9dcb1
https://pubmed.ncbi.nlm.nih.gov/17328773
https://pubmed.ncbi.nlm.nih.gov/17328773
Publikováno v:
Progress in brain research. 127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a056752b49871cac8c7932eb6e218b02
https://pubmed.ncbi.nlm.nih.gov/11142043
https://pubmed.ncbi.nlm.nih.gov/11142043
Publikováno v:
Investigative ophthalmologyvisual science. 41(12)
To apply noninvasive tests for examining visual and other sensory functions of pigmented Royal College of Surgeons (RCS) rats compared with pigmented and albino control animals.Rats aged 3 and 7 months were tested with a general neurologic examinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::296276da9b77474540738591648cce26
https://pubmed.ncbi.nlm.nih.gov/11053302
https://pubmed.ncbi.nlm.nih.gov/11053302