Zobrazeno 1 - 3
of 3
pro vyhledávání: '"R D, Friberg"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 78:1403-1410
GH concentration profiles in patients with acromegaly are characterized by rapid GH pulsatility and high interpulse GH concentrations. Animal and human studies have shown that GH pulses are consequent upon periodic discharges of hypothalamic GHRH, wh
Publikováno v:
The Journal of clinical endocrinology and metabolism. 82(10)
Pituitary irradiation suppresses GH hypersecretion in patients with acromegaly. Within 10 yr after radiotherapy, up to 80% of patients achieve plasma GH levels below 5 micrograms/L. Whether this is sufficient to normalize plasma insulin-like growth f
Publikováno v:
The American journal of physiology. 265(2 Pt 1)
Growth hormone-releasing hormone (GHRH) has been shown in vitro to increase proliferation of pituitary somatotrophs, to increase transcription of the GH gene, to promote accumulation of GH mRNA, and to stimulate GH release. The in vivo involvement of