Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R D, Eckardt"'
Publikováno v:
European Journal of Pharmacology. 183:1872-1873
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a812c300c3446b0ccdad8e55e9c8ab7a
https://doi.org/10.1016/0014-2999(90)92208-z
https://doi.org/10.1016/0014-2999(90)92208-z
Publikováno v:
Journal of Biological Chemistry. 262:1590-1595
omega-Hydroxylation of leukotriene B4 (LTB4) has been reported in human and rodent polymorphonuclear leukocytes; preliminary information indicates that this metabolism is cytochrome P-450 dependent. Therefore, these studies were initiated to characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ba6836975128445447dacf7f82fcc9
https://doi.org/10.1016/s0021-9258(19)75676-2
https://doi.org/10.1016/s0021-9258(19)75676-2
Publikováno v:
Annals of the New York Academy of Sciences. 524:423-425
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a0cef61a639a69cf377bb6160b58d1b
https://doi.org/10.1111/j.1749-6632.1988.tb38575.x
https://doi.org/10.1111/j.1749-6632.1988.tb38575.x
Publikováno v:
Circulatory shock. 25(1)
The purpose of this study was to examine the effects of the peptidoleukotriene receptor antagonist, SKF 104353, on the responses to endotoxin in conscious male Sprague-Dawley rats. Administration of Salmonella enteritidis endotoxin (30 mg/kg i.v.; LD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f45b9c2a3772066fdf84b38506d4920f
https://pubmed.ncbi.nlm.nih.gov/3042186
https://pubmed.ncbi.nlm.nih.gov/3042186
Autor:
J F, Newton, K M, Straub, R H, Dewey, C D, Perchonock, T B, Leonard, M E, McCarthy, J G, Gleason, R D, Eckardt
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 15(2)
In vivo experiments indicate that the major route of metabolism of SKF 102,081 [5-(2-dodecylphenyl)-4,6-dithianonanedioic acid] is via omega-oxidation and subsequent beta-oxidation. Therefore, in vitro experiments were designed to characterize the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbed507e41c51ba4b47924d0d74e02a6
https://pubmed.ncbi.nlm.nih.gov/2882972
https://pubmed.ncbi.nlm.nih.gov/2882972
Publikováno v:
The Journal of biological chemistry. 262(4)
omega-Hydroxylation of leukotriene B4 (LTB4) has been reported in human and rodent polymorphonuclear leukocytes; preliminary information indicates that this metabolism is cytochrome P-450 dependent. Therefore, these studies were initiated to characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8117d9254296830b0193c3b8297bcbed
https://pubmed.ncbi.nlm.nih.gov/3027095
https://pubmed.ncbi.nlm.nih.gov/3027095
Publikováno v:
Eicosanoids. 2(2)
Endotoxemia is associated with increases in a number of humoral mediators including vasopressin, thromboxane and leukotrienes (LT), all of which may participate in the pathophysiologic responses to endotoxemia. Previous studies from our laboratory de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff82da7fa525793e1a953e0eced0e2c7
https://pubmed.ncbi.nlm.nih.gov/2560662
https://pubmed.ncbi.nlm.nih.gov/2560662
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 249(3)
The purpose of these experiments was to investigate the effects of the selective peptidoleukotriene receptor antagonist, SKF 104353, on leukotriene (LT)C4, LTD4 and LTE4 vasopressor responses in conscious, normotensive rats. Steady-state plasma conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f03e8a3fd93e81043bfbe66e552d56ee
https://pubmed.ncbi.nlm.nih.gov/2543811
https://pubmed.ncbi.nlm.nih.gov/2543811
Autor:
L. M. Hillegass, E. F. Smith, Egan Jw, J F Newton, M.J. Slivjak, Don E. Griswold, R. D. Eckardt
Publikováno v:
Prostaglandins. 37(5)
This study was designed to assess the effect of a peptidoleukotriene receptor antagonist, SKF 104353, for limiting myocardial damage and neutrophil accumulation in rats subjected to myocardial reperfusion injury (MI/R). In conscious rats, SKF 10,4353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b4de94e75c55bc7e5a8eb35ddf7a1a
https://pubmed.ncbi.nlm.nih.gov/2544926
https://pubmed.ncbi.nlm.nih.gov/2544926