Zobrazeno 1 - 10
of 56
pro vyhledávání: '"R D, Cardiff"'
Publikováno v:
Journal of mammary gland biology and neoplasia. 5(4)
Foci of atypical mammary epithelium have been associated with breast cancer in many species including mouse and man. The advent of targeted genomics has led to the creation of numerous genetically engineered mice (GEM) which display focal atypical le
Autor:
E, Landesman-Bollag, D H, Song, R, Romieu-Mourez, D J, Sussman, R D, Cardiff, G E, Sonenshein, D C, Seldin
Publikováno v:
Molecular and cellular biochemistry. 227(1-2)
Breast cancer is a major cause of cancer death in women, and the genetic abnormalities leading to the common sporadic forms of the disease are still under active investigation. CK2 has been reported to be upregulated in human breast cancer, which the
Autor:
M, Gadd, C, Pisc, J, Branda, V, Ionescu-Tiba, Z, Nikolic, C, Yang, T, Wang, G M, Shackleford, R D, Cardiff, E V, Schmidt
Publikováno v:
Cancer research. 61(24)
A coordinated growth arrest during mammary involution completes the dramatic changes in mammary cell proliferation seen during pregnancy and lactation. Signals regulating this arrest are poorly understood, despite their potential relevance to oncogen
Autor:
Y, Hosokawa, A, Papanikolaou, R D, Cardiff, K, Yoshimoto, M, Bernstein, T C, Wang, E V, Schmidt, A, Arnold
Publikováno v:
Transgenic research. 10(5)
Overexpression of the cyclin D1 oncogene and inactivation of the p53 tumor suppressor have both been implicated in substantial proportions of sporadic human breast cancers. Transgenic mice with cyclin D1 overexpression targeted to mammary tissue by t
Publikováno v:
Cancer research. 61(8)
Treatment of female C57BL/6J (B6) mice carrying the mutant Min allele of the adenomatous polyposis coli (Apc) gene with ethylnitrosourea (ENU) results in approximately 90% of mice developing an average of three mammary tumors within 65 days. As a fir
Publikováno v:
Cancer research. 61(5)
Werner syndrome is an autosomal recessive disorder characterized by genomic instability and by the premature onset of a number of age-related diseases, including malignancy. To assess a potential collaboration between p21 or p53 cell cycle regulators
Publikováno v:
Cancer research. 61(1)
The transcription factor, CCAAT/enhancer binding protein beta (C/EBPbeta), regulates the expression of genes involved in proliferation and terminal differentiation. Dimerization of the dominant-negative C/EBPbeta-liver-enriched inhibitory protein (LI
Autor:
R D, Cardiff
Publikováno v:
Microscopy research and technique. 52(2)
In March 1999, a panel of distinguished pathologists was convened by the U.S. National Institutes of Health Breast Cancer Think Tank to develop a classification of breast lesions based on their examination of 39 models of Genetically Engineered Mice
Publikováno v:
Journal of mammary gland biology and neoplasia. 5(2)
This article introduces a CD-ROM containing whole-mount and histological images of normal growth and development of both the mouse mammary gland and the human breast. It also covers nonneoplastic lesions and neoplasias in both species including a cat
Autor:
Y, Wang, S W, Hayward, A A, Donjacour, P, Young, T, Jacks, J, Sage, R, Dahiya, R D, Cardiff, M L, Day, G R, Cunha
Publikováno v:
Cancer research. 60(21)
The retinoblastoma (Rb) gene product is a prototypic tumor suppressor. Mice lacking the Rb gene are not viable and die in utero at approximately 13 days of gestation. In this study, we have rescued Rb-/- prostates by grafting pelvic organ rudiments f