Zobrazeno 1 - 10
of 43
pro vyhledávání: '"R D, Braun"'
Publikováno v:
Veterinary anaesthesia and analgesia. 27(2)
Autor:
Mark W. Dewhirst, Rachel A. Richardson, R. D. Braun, Pierre Sonveaux, Timothy J. McMahon, Andrew M. Kaz, John R. Pawloski, Gillian M. Tozer, Jonathan S. Stamler, Stacey A. Snyder, Joseph Bonaventura, L. Isabel Cárdenas-Navia
Publikováno v:
Circulation Research. 96:1119-1126
In erythrocytes, S -nitrosohemoglobin (SNO-Hb) arises from S -nitrosylation of oxygenated hemoglobin (Hb). It has been shown that SNO-Hb behaves as a nitric oxide (NO) donor at low oxygen tensions. This property, in combination with oxygen transport
Publikováno v:
British Journal of Cancer
The effects of intravenous diethylamine/nitric oxide (DEA/NO), a short-acting nitric oxide (NO) donor, on systemic haemodynamics, muscle and tumour blood flow (MBF and TBF) and tumour oxygenation were examined in rats bearing subcutaneous R3230Ac car
Publikováno v:
Microvascular Research. 44:73-84
Oxygen tension was recorded with double-barreled microelectrodes in the retina of anesthetized cats and monkeys. The oxygen tension (PO2) was often observed to undergo spontaneous irregular fluctuations with peak-to-peak amplitudes of about 3 to as m
Publikováno v:
Journal of Applied Physiology. 72:1960-1968
We have studied the conditions under which a perfluorocarbon emulsion of perfluorooctyl bromide (PFOB; Alliance Pharmaceutical, San Diego, CA) enhances tissue O2 delivery. Measurements of retinal tissue O2 tension (PO2) were made in anesthetized, art
Autor:
Robert A. Linsenmeier, R. D. Braun
Publikováno v:
The Journal of General Physiology
Oxygen tension (PO2) was measured with microelectrodes within the retina of anesthetized cats during normoxia and hypoxemia (i.e., systemic hypoxia), and photoreceptor oxygen consumption was determined by fitting PO2 measurements to a model of steady
Publikováno v:
Photochemistry and photobiology. 74(5)
Photodynamic therapy (PDT) with verteporfin provides a reliable way to destroy malignant tissues. Changes in the blood flow and oxygen partial pressure (pO2) during verteporfin-PDT were studied here in the tumor tissue of the rat mammary R3230Ac carc
Publikováno v:
Cancer research. 61(7)
The efficacy of novel cancer therapeutics can be hampered by inefficient delivery of agents to the tumor at effective concentrations. Liposomes have been used as a method to overcome some delivery issues and, in combination with hyperthermia, have be
Publikováno v:
SPIE Proceedings.
Measurements of tissue oxygen partial pressure (pO2), blood flow and blood pressure were recorded in rat mammary R323OAc tumors during treatment with verteporfin-based photodynamic therapy. Microelectrodes of 12 micron tip diameter were used in a fix
Publikováno v:
Cancer research. 60(24)
The tumor drug concentrations, drug distributions, and therapeutic efficacies achieved by three fundamentally different liposomes, nonthermosensitive liposome (NTSL), traditional thermosensitive liposome (TTSL), and low temperature sensitive liposome