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Autor:
J L, Cunha, F C, Soardi, R D, Bernardi, L E C, Oliveira, C E, Benedetti, G, Guerra-Junior, A T, Maciel-Guerra, M P, de Mello
Publikováno v:
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 44(4)
Male sex determination in humans is controlled by the SRY gene, which encodes a transcriptional regulator containing a conserved high mobility group box domain (HMG-box) required for DNA binding. Mutations in the SRY HMG-box affect protein function,