Zobrazeno 1 - 10
of 132
pro vyhledávání: '"R Clay Reid"'
Autor:
Sven Dorkenwald, Nicholas L Turner, Thomas Macrina, Kisuk Lee, Ran Lu, Jingpeng Wu, Agnes L Bodor, Adam A Bleckert, Derrick Brittain, Nico Kemnitz, William M Silversmith, Dodam Ih, Jonathan Zung, Aleksandar Zlateski, Ignacio Tartavull, Szi-Chieh Yu, Sergiy Popovych, William Wong, Manuel Castro, Chris S Jordan, Alyssa M Wilson, Emmanouil Froudarakis, JoAnn Buchanan, Marc M Takeno, Russel Torres, Gayathri Mahalingam, Forrest Collman, Casey M Schneider-Mizell, Daniel J Bumbarger, Yang Li, Lynne Becker, Shelby Suckow, Jacob Reimer, Andreas S Tolias, Nuno Macarico da Costa, R Clay Reid, H Sebastian Seung
Publikováno v:
eLife, Vol 11 (2022)
Learning from experience depends at least in part on changes in neuronal connections. We present the largest map of connectivity to date between cortical neurons of a defined type (layer 2/3 [L2/3] pyramidal cells in mouse primary visual cortex), whi
Externí odkaz:
https://doaj.org/article/27b1354692bd4be48848ffb48a230736
Autor:
Gayathri Mahalingam, Russel Torres, Daniel Kapner, Eric T Trautman, Tim Fliss, Shamishtaa Seshamani, Eric Perlman, Rob Young, Samuel Kinn, JoAnn Buchanan, Marc M Takeno, Wenjing Yin, Daniel J Bumbarger, Ryder P Gwinn, Julie Nyhus, Ed Lein, Steven J Smith, R Clay Reid, Khaled A Khairy, Stephan Saalfeld, Forrest Collman, Nuno Macarico da Costa
Publikováno v:
eLife, Vol 11 (2022)
Serial-section electron microscopy (ssEM) is the method of choice for studying macroscopic biological samples at extremely high resolution in three dimensions. In the nervous system, nanometer-scale images are necessary to reconstruct dense neural wi
Externí odkaz:
https://doaj.org/article/bd5f8cd87b2346a0937e74c351b6c225
Autor:
Casey M Schneider-Mizell, Agnes L Bodor, Forrest Collman, Derrick Brittain, Adam Bleckert, Sven Dorkenwald, Nicholas L Turner, Thomas Macrina, Kisuk Lee, Ran Lu, Jingpeng Wu, Jun Zhuang, Anirban Nandi, Brian Hu, JoAnn Buchanan, Marc M Takeno, Russel Torres, Gayathri Mahalingam, Daniel J Bumbarger, Yang Li, Thomas Chartrand, Nico Kemnitz, William M Silversmith, Dodam Ih, Jonathan Zung, Aleksandar Zlateski, Ignacio Tartavull, Sergiy Popovych, William Wong, Manuel Castro, Chris S Jordan, Emmanouil Froudarakis, Lynne Becker, Shelby Suckow, Jacob Reimer, Andreas S Tolias, Costas A Anastassiou, H Sebastian Seung, R Clay Reid, Nuno Maçarico da Costa
Publikováno v:
eLife, Vol 10 (2021)
Inhibitory neurons in mammalian cortex exhibit diverse physiological, morphological, molecular, and connectivity signatures. While considerable work has measured the average connectivity of several interneuron classes, there remains a fundamental lac
Externí odkaz:
https://doaj.org/article/7183b51f322941cfadb44572b84338f8
Autor:
Lawrence Huang, Peter Ledochowitsch, Ulf Knoblich, Jérôme Lecoq, Gabe J Murphy, R Clay Reid, Saskia EJ de Vries, Christof Koch, Hongkui Zeng, Michael A Buice, Jack Waters, Lu Li
Publikováno v:
eLife, Vol 10 (2021)
Fluorescent calcium indicators are often used to investigate neural dynamics, but the relationship between fluorescence and action potentials (APs) remains unclear. Most APs can be detected when the soma almost fills the microscope’s field of view,
Externí odkaz:
https://doaj.org/article/82e769b44ca8434cb6517c2168640eea
Autor:
Anton Arkhipov, Nathan W Gouwens, Yazan N Billeh, Sergey Gratiy, Ramakrishnan Iyer, Ziqiang Wei, Zihao Xu, Reza Abbasi-Asl, Jim Berg, Michael Buice, Nicholas Cain, Nuno da Costa, Saskia de Vries, Daniel Denman, Severine Durand, David Feng, Tim Jarsky, Jérôme Lecoq, Brian Lee, Lu Li, Stefan Mihalas, Gabriel K Ocker, Shawn R Olsen, R Clay Reid, Gilberto Soler-Llavina, Staci A Sorensen, Quanxin Wang, Jack Waters, Massimo Scanziani, Christof Koch
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 11, p e1006535 (2018)
Despite advances in experimental techniques and accumulation of large datasets concerning the composition and properties of the cortex, quantitative modeling of cortical circuits under in-vivo-like conditions remains challenging. Here we report and p
Externí odkaz:
https://doaj.org/article/574a2817931b457b9ef5252488b72b54
Autor:
Timothy J Lee, Aditi Kumar, Aishwarya H Balwani, Derrick Brittain, Sam Kinn, Craig A Tovey, Eva L Dyer, Nuno M da Costa, R Clay Reid, Craig R Forest, Daniel J Bumbarger
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206172 (2018)
Serial section transmission electron microscopy (ssTEM) is the most promising tool for investigating the three-dimensional anatomy of the brain with nanometer resolution. Yet as the field progresses to larger volumes of brain tissue, new methods for
Externí odkaz:
https://doaj.org/article/2de3ad31454a404085f5ae6ca5b6a208
Autor:
Daniel J Denman, Jennifer A Luviano, Douglas R Ollerenshaw, Sissy Cross, Derric Williams, Michael A Buice, Shawn R Olsen, R Clay Reid
Publikováno v:
eLife, Vol 7 (2018)
Mammalian visual behaviors, as well as responses in the neural systems underlying these behaviors, are driven by luminance and color contrast. With constantly improving tools for measuring activity in cell-type-specific populations in the mouse durin
Externí odkaz:
https://doaj.org/article/65496cc8a8e749f0989262cb2279e884
Autor:
Brendan Celii, Stelios Papadopoulos, Zhuokun Ding, Paul G. Fahey, Eric Wang, Christos Papadopoulos, Alexander B. Kunin, Saumil Patel, J. Alexander Bae, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Erick Cobos, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, Casey M. Schneider-Mizell, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Szi-chieh Yu, Wenjing Yin, Daniel Xenes, Lindsey M. Kitchell, Patricia K. Rivlin, Victoria A. Rose, Caitlyn A. Bishop, Brock Wester, Emmanouil Froudarakis, Edgar Y. Walker, Fabian Sinz, H. Sebastian Seung, Forrest Collman, Nuno Maçarico da Costa, R. Clay Reid, Xaq Pitkow, Andreas S. Tolias, Jacob Reimer
We are now in the era of millimeter-scale electron microscopy (EM) volumes collected at nanometer resolution (Shapson-Coe et al., 2021; Consortium et al., 2021). Dense reconstruction of cellular compartments in these EM volumes has been enabled by re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d21e2f4dd35616cabd72c4d26678fa28
https://doi.org/10.1101/2023.03.14.532674
https://doi.org/10.1101/2023.03.14.532674
Autor:
Zhuokun Ding, Paul G. Fahey, Stelios Papadopoulos, Eric Y. Wang, Brendan Celii, Christos Papadopoulos, Alexander B. Kunin, Andersen Chang, Jiakun Fu, Zhiwei Ding, Saumil Patel, Kayla Ponder, Taliah Muhammad, J. Alexander Bae, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Erick Cobos, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, Casey M. Schneider-Mizell, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Wenjing Yin, Szi-chieh Yu, Emmanouil Froudarakis, Fabian Sinz, H. Sebastian Seung, Forrest Collman, Nuno Maçarico da Costa, R. Clay Reid, Edgar Y. Walker, Xaq Pitkow, Jacob Reimer, Andreas S. Tolias
Publikováno v:
bioRxiv
To understand how the neocortex underlies our ability to perceive, think, and act, it is important to study the relationship between circuit connectivity and function. Previous research has shown that excitatory neurons in layer 2/3 of the primary vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f49ecf14e08fe0585dc044ffb41c11
https://europepmc.org/articles/PMC10054929/
https://europepmc.org/articles/PMC10054929/
Autor:
Marissa A. Weis, Stelios Papadopoulos, Laura Hansel, Timo Lüddecke, Brendan Celii, Paul G. Fahey, J. Alexander Bae, Agnes L. Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J. Bumbarger, Manuel A. Castro, Forrest Collman, Nuno Maçarico da Costa, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, R. Clay Reid, Casey M. Schneider-Mizell, H. Sebastian Seung, William Silversmith, Marc Takeno, Russel Torres, Nicholas L. Turner, William Wong, Jingpeng Wu, Wenjing Yin, Szi-chieh Yu, Jacob Reimer, Andreas S. Tolias, Alexander S. Ecker
Neurons in the neocortex exhibit astonishing morphological diversity which is critical for properly wiring neural circuits and giving neurons their functional properties. The extent to which the morphological diversity of excitatory neurons forms a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86365cd9ecb9a14800b6686d516cd357
https://doi.org/10.1101/2022.12.22.521541
https://doi.org/10.1101/2022.12.22.521541