Zobrazeno 1 - 10
of 125
pro vyhledávání: '"R Christopher Pierce"'
Autor:
Khampaseuth Rasakham, Heath D Schmidt, Kevin Kay, Megan N Huizenga, Narghes Calcagno, R Christopher Pierce, Tara L Spires-Jones, Ghazaleh Sadri-Vakili
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102524 (2014)
Chronic cocaine exposure in both human addicts and in rodent models of addiction reduces prefrontal cortical activity, which subsequently dysregulates reward processing and higher order executive function. The net effect of this impaired gating of be
Externí odkaz:
https://doaj.org/article/0c091ee2dd6b4aefa220fa9cd236a578
Autor:
Sarah E. Swinford-Jackson, Matthew T. Rich, Phillip J. Huffman, Melissa C. Knouse, Arthur S. Thomas, Sharvari Mankame, Samantha J. Worobey, R. Christopher Pierce
Publikováno v:
Addiction Neuroscience, Vol 9, Iss , Pp 100133- (2023)
The present study examined the effect of deep brain stimulation (DBS) in the nucleus accumbens shell on cocaine seeking and neuronal plasticity in rats. Electrical DBS of the accumbens shell attenuated cocaine primed reinstatement across a range of f
Externí odkaz:
https://doaj.org/article/ed7c0806d221408faee4382070eaf22e
Publikováno v:
Neuron. 111:1351-1353
Autor:
Sarah E. Swinford-Jackson, Phillip J. Huffman, Melissa C. Knouse, Arthur S. Thomas, Matthew T. Rich, Sharvari Mankame, Samantha J. Worobey, Mateo Sarmiento, Ayanna Coleman, R. Christopher Pierce
Publikováno v:
Neuropsychopharmacology. 48:459-467
Autor:
Sarah E. Swinford-Jackson, Bruno Fant, Mathieu E. Wimmer, Donovan Chan, Melissa C. Knouse, Mateo Sarmiento, Arthur S. Thomas, Phillip J. Huffman, Sharvari Mankame, Samantha J. Worobey, R. Christopher Pierce
Publikováno v:
J Neurosci
ORCID
PubMed Central
ORCID
PubMed Central
Paternal environmental perturbations can influence the physiology and behavior of offspring. For example, our previous work showed reduced cocaine reinforcement in male, but not female, progeny of rat sires that self-administered cocaine. The informa
Autor:
Sarah E. Swinford-Jackson, Matthew T. Rich, Phillip J. Huffman, Melissa C. Knouse, Arthur S. Thomas, Sharvari Mankame, Samantha J. Worobey, R. Christopher Pierce
Publikováno v:
bioRxiv
BackgroundClinically, deep brain stimulation (DBS) utilizes relatively high frequencies (>100 Hz). In preclinical models, 160 Hz stimulation of the nucleus accumbens in rodents prevents relapse of drug seeking. However, the ability of varied frequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a942ea8ff1413e381f025d2e97599028
https://doi.org/10.1101/2023.01.23.524956
https://doi.org/10.1101/2023.01.23.524956
Autor:
John J. Maurer, Mathieu E. Wimmer, Christopher A. Turner, Rae J. Herman, Yafang Zhang, Kael Ragnini, Julia Ferrante, Blake A. Kimmey, Richard C. Crist, R. Christopher Pierce, Heath D. Schmidt
Publikováno v:
Mol Psychiatry
Nicotine intake, whether through tobacco smoking or e-cigarettes, remains a global health concern. An emerging preclinical literature indicates that parental nicotine exposure produces behavioral, physiological, and molecular changes in subsequent ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65e9a99f4322cb7baf7363e286f83c8
https://europepmc.org/articles/PMC9675874/
https://europepmc.org/articles/PMC9675874/
Autor:
Kael H. Ragnini, Yafang Zhang, Kyla D. Mace, R. Christopher Pierce, Matthew T. Rich, Heath D. Schmidt, Vanessa Weir, Riley Merkel, Nicole S. Hernandez
Publikováno v:
Molecular psychiatry
An emerging preclinical literature suggests that targeting central glucagon-like peptide-1 receptors (GLP-1Rs) may represent a novel approach to treating cocaine use disorder. However, the exact neural circuits and cell types that mediate the suppres
Autor:
Mathieu E. Wimmer, Allison M. Bond, Marco D. Carpenter, Hongjun Song, Sonia I. Lombroso, Kyle S. Czarnecki, Qiwen Hu, Elizabeth A. Heller, R. Christopher Pierce, Carissa J. Lim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Endogenous homeostatic mechanisms can restore normal neuronal function following cocaine-induced neuroadaptations. Such mechanisms may be exploited to develop novel therapies for cocaine addiction, but a molecular target has not yet been identified.
Autor:
Duncan Van Nest, John J Maurer, Bruno Fant, Sarah E. Swinford-Jackson, R. Christopher Pierce, Mathieu E. Wimmer
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Although the influence of gestational cocaine exposure on offspring has been the focus of a sustained research effort, the effect of preconception cocaine self-administration by dams on progeny has received far less attention. METHOD: In t