Zobrazeno 1 - 10
of 189
pro vyhledávání: '"R Chicheportiche"'
Autor:
L. Gruaz, Danielle Burger, M.‐T. Kaufmann, S. Benavent, R. Chicheportiche, Jean-Michel Dayer, N. Begué‐Pastor
OBJECTIVES To investigate the effects of the active metabolite of leflunomide, A77 1726, on fibroblast-like synoviocytes. In rheumatoid arthritis (RA) synoviocytes participate in tissue destruction by producing metalloproteinases (MMP), prostaglandin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0636dd4fd0f1e8ce17d7a26f5f94e7ec
http://doc.rero.ch/record/299505/files/420089.pdf
http://doc.rero.ch/record/299505/files/420089.pdf
Publikováno v:
Europe PubMed Central
Chemokines and adhesion molecules such as integrins play a major part in the trafficking, extravasation, and recruitment of leukocytes to inflammatory sites. This study investigated the effects of beta(2) integrin engagement on chemokine production b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1950fe618f9b1e71d31261d1d90d35cd
https://doi.org/10.1182/blood.v97.10.2932
https://doi.org/10.1182/blood.v97.10.2932
Publikováno v:
Blood. 95:3868-3877
beta2 integrins are involved in the recruitment of leukocytes to inflammatory sites and in cellular activation. We demonstrate that ligation of CD11b (Mac-1, CR3) or CD11c (p150, CR4) alpha chains of beta2 integrins by mAbs or soluble chimeric CD23 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089e7d52c984631301b1fa705da55ffe
https://doi.org/10.1182/blood.v95.12.3868.012k43_3868_3877
https://doi.org/10.1182/blood.v95.12.3868.012k43_3868_3877
Autor:
Christian Frelin, Georges Romey, Michel Fosset, M. Balerna, Jean-François Renaud, Hugues Schweitz, Jean-Pierre Vincent, R. Chicheportiche, Gilles Ponzio, Jacques Barhanin, M Lazdunski, Alain Lombet, Y. Jacques, J. Pouysségur
Publikováno v:
Neurochemistry international.
This paper describes how neurotoxins specific of the Na(+) channel are used to study its function, its structure and its differentiation in a variety of excitable and non-impulsive cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db096c7ecda7d74eeec4f9ddd2a74531
https://pubmed.ncbi.nlm.nih.gov/20487771
https://pubmed.ncbi.nlm.nih.gov/20487771
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(2)
Besides its actions on the regulation of appetite, leptin has also been implicated in regulating reproductive and immune functions. Because leptin-deficient mice are more susceptible to lipopolysaccharide- and tumor necrosis factor-alpha-induced shoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e43e6bd1513c2b5e7e3393735eba4761
https://pubmed.ncbi.nlm.nih.gov/11158047
https://pubmed.ncbi.nlm.nih.gov/11158047
Autor:
T J, Smeets, J M, Dayer, M C, Kraan, J, Versendaal, R, Chicheportiche, F C, Breedveld, P P, Tak
Publikováno v:
Arthritis and rheumatism. 43(2)
Interferon-beta (IFNbeta) treatment is emerging as a potentially effective form of therapy in various immune-mediated conditions. This study evaluated the effects of IFNbeta therapy on the cell infiltrate, cytokine profile, and expression of metallop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a39f1dfd2473f48dcb2c0d4c829da204
https://pubmed.ncbi.nlm.nih.gov/10693865
https://pubmed.ncbi.nlm.nih.gov/10693865
Human mononuclear phagocytes can modulate the turnover of extracellular matrix by producing metalloproteinases such as 92-kD gelatinase and interstitial collagenase as well as the tissue inhibitor of metalloproteinases (TIMP). We have previously repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f27012bba3c735621bde06a6964e0a
https://europepmc.org/articles/PMC185881/
https://europepmc.org/articles/PMC185881/
Publikováno v:
Nuclear medicine and biology. 20(6)
In an attempt to visualize in vivo the dopamine transporter and evaluate its potential as an imaging tool for monitoring dopamine fiber degeneration by positron emission tomography, the 18F-positron-emitting analogue of 3-fluoromethyl-1-[1-(2-benzoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d3738cc83a3ecc3c11bfc166e3df6e
https://pubmed.ncbi.nlm.nih.gov/8401373
https://pubmed.ncbi.nlm.nih.gov/8401373
Autor:
Nicolò Costantino Brembilla, Matthes T, J-M Ramirez, Jm Dayer, J-H Saurat, Carlo Chizzolini, E. Roosnek, R Chicheportiche, Olivier Sorg
Publikováno v:
Annals of the Rheumatic Diseases. 69:A74-A74
Ligands of the aryl hydrocarbon receptor (AHR), a transcription factor mediating dioxin effects, favour Th17 cell differentiation and exacerbate autoimmunity in mice. The authors investigated how AHR ligands affect human T cell polarisation. The high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9068b192e460df1beb2e26a70871475f
https://doi.org/10.1136/ard.2010.129668y
https://doi.org/10.1136/ard.2010.129668y
Effects of eleven cytokines and of IL-1 and tumor necrosis factor inhibitors in a human B cell assay
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 148(9)
The effects of different recombinant human cytokines and cytokine inhibitors were compared in a culture system in which cell contact with mutant EL-4 thymoma cells of murine origin efficiently stimulates human B cell proliferation and Ig secretion in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c849f9a4039e29a4527ce0886ce3b88a
https://pubmed.ncbi.nlm.nih.gov/1315359
https://pubmed.ncbi.nlm.nih.gov/1315359