Zobrazeno 1 - 10
of 451
pro vyhledávání: '"R Caso"'
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Parkinson´s disease (PD), the second most common neurodegenerative disease in the world, is characterized by the death or impairment of dopaminergic neurons (DAn) in the substantia nigra pars compacta and dopamine depletion in th
Externí odkaz:
https://doaj.org/article/b5277021b1b14fbf96f0455273878e46
Autor:
Cristina Ulecia-Morón, Álvaro G. Bris, Karina Macdowell, Mónica Movilla-Pérez, Marta P. Pereira, Juan C. Leza, Javier R. Caso
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S655- (2023)
Externí odkaz:
https://doaj.org/article/e465dc6dc8c54944977cf7437d3c6967
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/90c41bdaee40401a8ddddf7550cb055e
Autor:
David Martín-Hernández, Irene L. Gutiérrez, Marta González-Prieto, Karina S. MacDowell, Javier Robledo-Montaña, Hiram Tendilla-Beltrán, Natalia Calleja-Rodríguez, Álvaro G. Bris, Cristina Ulecia-Morón, Beatriz Moreno, Javier R. Caso, Borja García-Bueno, Sandra Rodrigues-Mascarenhas, Ignacio Marín-Jiménez, Juan Carlos Leza, Luis Menchén
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The chronic inflammatory process that characterizes inflammatory bowel diseases (IBD) is mainly driven by T-cell response to microbial and environmental antigens. Psychological stress is a potential trigger of clinical flares of IBD, and sph
Externí odkaz:
https://doaj.org/article/edc521850f6e4ccab60422df1f7b17cc
Autor:
David Martín-Hernández, Marina Muñoz-López, Hiram Tendilla-Beltrán, Javier R. Caso, Borja García-Bueno, Luis Menchén, Juan C. Leza
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12634 (2023)
Over the past few decades, extensive research has shed light on immune alterations and the significance of dysfunctional biological barriers in psychiatric disorders. The leaky gut phenomenon, intimately linked to the integrity of both brain and inte
Externí odkaz:
https://doaj.org/article/b3b87dc972cd4d3f9ba7729e2cae5575
Autor:
Javier R. Caso, Karina S. MacDowell, Ana González-Pinto, Saínza García, Javier de Diego-Adeliño, Mar Carceller-Sindreu, Fernando Sarramea, Javier Caballero-Villarraso, Patricia Gracia-García, Concepción De la Cámara, Luis Agüera, María L. Gómez-Lus, Claudio Alba, Juan M. Rodríguez, Juan C. Leza
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Although alterations in the gut microbiota have been linked to the pathophysiology of major depressive disorder (MDD), including through effects on the immune response, our understanding is deficient about the straight connection patterns am
Externí odkaz:
https://doaj.org/article/923dbf1f394842af9740797129206d51
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1e8e28b02b4f4c33942583e08a4dcd46
Autor:
Javier R. Caso, Karina S. MacDowell, Marta Soto, Francisco Ruiz-Guerrero, Álvaro Carrasco-Díaz, Juan C. Leza, José L. Carrasco, Marina Díaz-Marsá
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The attempts to clarify the origin of eating disorders (ED) have not been completely successful and their etiopathogenesis remains unknown. Current research shows an activation of the immune response in neuropsychiatric diseases, including ED. We aim
Externí odkaz:
https://doaj.org/article/bb5ebb1fd1194a35a434d5a310617bc7
Autor:
Alejandra Vargas-Caraveo, Aline Sayd, Javier Robledo-Montaña, Javier R. Caso, José L. M. Madrigal, Borja García-Bueno, Juan C. Leza
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-17 (2020)
Abstract Background The circumventricular organs (CVOs) are blood-brain-barrier missing structures whose activation through lipopolysaccharide (LPS) is a starting point for TLR-driven (Toll-like receptors) neuroinflammation. The aim of this study was
Externí odkaz:
https://doaj.org/article/ae2639563b0d45ffb9562195aa764ae1
Autor:
Irene L. Gutiérrez, Cinzia Dello Russo, Fabiana Novellino, Javier R. Caso, Borja García-Bueno, Juan C. Leza, José L. M. Madrigal
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6143 (2022)
A growing body of evidence demonstrates the important role of the noradrenergic system in the pathogenesis of many neurodegenerative processes, especially Alzheimer’s disease, due to its ability to control glial activation and chemokine production
Externí odkaz:
https://doaj.org/article/ad8b2b9266f84f0ab5f2e009fa7273d4