Zobrazeno 1 - 10
of 17
pro vyhledávání: '"R C Tam"'
Publikováno v:
The Journal of Immunology. 163:3709-3717
We previously described the promotion of type 1 cytokine responses by the nucleoside analogue, ribavirin, in human T cells in vitro. In this study, we examined whether type 1 cytokine polarization by ribavirin in vivo could promote contact hypersensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4836eeb2d1d6bc3509d5a23450ad3707
https://doi.org/10.4049/jimmunol.163.7.3709
https://doi.org/10.4049/jimmunol.163.7.3709
Publikováno v:
The Journal of Immunology. 158:200-208
Ligation of CD28 provides a costimulatory signal essential for Ag-mediated T cell activation via the TCR. Blocking CD28 ligation can inhibit cytokine expression and elicits a state of T cell hyporesponsiveness. In this study, we examined the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf0a7ef80ba4ee63361c4953f584363c
https://doi.org/10.4049/jimmunol.158.1.200
https://doi.org/10.4049/jimmunol.158.1.200
Publikováno v:
The Journal of Immunology. 156:3765-3771
Although the current dogma of T cell recognition stresses its exquisite specificity, T cell clones selected for a given peptide can recognize other sequentially or structurally related peptides. Here, we have examined the immunogenicity and tolerogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07908464981f7bf4fa09be63249df7b4
https://doi.org/10.4049/jimmunol.156.10.3765
https://doi.org/10.4049/jimmunol.156.10.3765
Autor:
R. C. Tam, Marvin R. Garovoy, Geming Lui, Ying Li, C. A. Hunt, Sarah B. Noonberg, David G. Hwang
Publikováno v:
Nucleic Acids Research. 22:977-986
Augmented biological activity in vitro has been demonstrated in oligonucleotides (oligos) modified to provide nuclease resistance, to enhance cellular uptake or to increase target affinity. How chemical modification affects the duration of effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bec7a636e008304f9711c841dad3556
https://doi.org/10.1093/nar/22.6.977
https://doi.org/10.1093/nar/22.6.977
Autor:
M. B. Allen, T. W. Mackay, Michael Fitzpatrick, M Henley, C J Dore, P M Cotes, Neil J. Douglas, R C Tam, K. F. Whyte
Publikováno v:
Clinical Science. 84:319-324
1. To clarify the relationship between nocturnal oxygen desaturation and erythropoietin production in patients with chronic obstructive pulmonary disease, we determined arterial oxygen saturation and serum immunoreactive erythropoietin levels over 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63231089902a3f93be4f735d36b9097
https://doi.org/10.1042/cs0840319
https://doi.org/10.1042/cs0840319
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 156
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bedad98f4af9e442d1e8564302b93035
https://pubmed.ncbi.nlm.nih.gov/11068762
https://pubmed.ncbi.nlm.nih.gov/11068762
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(10)
Although the current dogma of T cell recognition stresses its exquisite specificity, T cell clones selected for a given peptide can recognize other sequentially or structurally related peptides. Here, we have examined the immunogenicity and tolerogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b18116c5b72b8255d5d84704669e7278
https://pubmed.ncbi.nlm.nih.gov/8621912
https://pubmed.ncbi.nlm.nih.gov/8621912
Publikováno v:
Transplantation. 61(5)
T cell tolerance to self-antigens is established through the recognition by immature T cells of dominant self-peptides presented in association with self-MHC molecules in the developing thymus (negative selection). The self-peptide Dd 61-80 is domina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e7014fee1528f6cc110a0ad3f04356b
https://pubmed.ncbi.nlm.nih.gov/8607166
https://pubmed.ncbi.nlm.nih.gov/8607166
Publikováno v:
British journal of haematology. 79(3)
Isoelectric focusing (IEF) in the pH range 2.5-5.0 has been used to compare the immunoreactive (ir) erythropoietin (Epo) in paired samples of serum and urine from three patients, two with idiopathic aplastic anaemia and one with paroxysmal nocturnal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9062eeeef8c78a234130683640fa11
https://pubmed.ncbi.nlm.nih.gov/1751380
https://pubmed.ncbi.nlm.nih.gov/1751380