Zobrazeno 1 - 10
of 31
pro vyhledávání: '"R C Siegel"'
Autor:
W C Bogard, S A Siegel, A O Leone, E Damiano, D J Shealy, T M Ely, B Frederick, M A Mascelli, R C Siegel, B Machielse
Publikováno v:
The Journal of Immunology. 150:4438-4449
HA-1A, a human IgM mAb, has been shown to significantly reduce mortality in septic patients with Gram-negative bacteremia, especially those with septic shock, in a controlled clinical trial. To confirm the reported specificity of this antibody for th
Autor:
R. Mehta, R. C. Siegel, T. Tram, Lawrence Steinman, Leslie J. Dorfman, Suzanne Hodgkinson, Mae Lim, J. W. Lindsey, Christopher Piercy, Dennis J. Mitchell, Dieter R. Enzmann
Publikováno v:
Neurology. 44(3 Pt 1)
We conducted an open trial of cM-T412, a chimeric monoclonal anti-CD4 antibody, in 29 patients with MS. This antibody caused a prompt and long-lasting depletion of circulating CD4 (helper/inducer) lymphocytes. The mean (±SE) CD4 count for the group
Autor:
W C, Bogard, S A, Siegel, A O, Leone, E, Damiano, D J, Shealy, T M, Ely, B, Frederick, M A, Mascelli, R C, Siegel, B, Machielse
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 150(10)
HA-1A, a human IgM mAb, has been shown to significantly reduce mortality in septic patients with Gram-negative bacteremia, especially those with septic shock, in a controlled clinical trial. To confirm the reported specificity of this antibody for th
Autor:
R C Siegel, R E Cathou
Publikováno v:
The Journal of Immunology. 125:1910-1915
Complexes of IgM equine anti-dansyl antibodies and different dansyl substituted carriers were tested for their ability to fix complement (C). Only dansyl92-Ficoll and dansyl12-poly-L-lysine were found to be effective. Dansyl13-bovine serum albumin, d
Autor:
R C Siegel
Publikováno v:
Journal of Biological Chemistry. 252:254-259
D-Pencillamine is believed to inhibit collagen cross-link biosynthesis by forming thiazolidine rings with lysyl-derived aldehydes that are intermediates in bifunctional cross-link synthesis. Recently, we showed that aldehyde biosynthesis catalyzed by
Autor:
R C, Siegel
Publikováno v:
Medical Clinics of North America. 61:283-297
Autor:
R. C. Siegel
Publikováno v:
Archives of Internal Medicine. 134:515-518
Autor:
J C Fu, R C Siegel
Publikováno v:
Journal of Biological Chemistry. 251:5779-5785
Lysyl oxidase is a specific amine oxidase that catalyzes the formation of aldehyde cross-link intermediates in collagen and elastin. In this study, lysyl oxidase from embryonic chick cartilage was purified to constant specific activity and a single p
Autor:
R C Siegel
Publikováno v:
Journal of Biological Chemistry. 251:5786-5792
In this paper, the synthesis of collagen cross-links in vitro was investigated in a defined system consisting of highly purified chick cartilage lysyl oxidase and chick bone collagen fibrils. Cross-link synthesis in vitro was quite similar to the bio
Publikováno v:
The Journal of Immunology. 127:2447-2452
We have examined the functional and hydrodynamic properties of the first component of human complement, C1, and the activated first component, C1-, reassembled in the presence of Ca++ from C1q and either the C1r2C1s2 or the C1r-2C1s-2 tetramer. Recon