Zobrazeno 1 - 10
of 37
pro vyhledávání: '"R C Puche"'
Publikováno v:
Drug Development and Industrial Pharmacy. 21:517-521
This paper reports data on the long term stability of the phosphorus-fluorine bond of sodium monofluorophosphate (MFP). Spontaneous hydrolysis of the drug in bulk form follows first order kinetics. Chemical stability, expressed as its t1/2, was found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74012144b20fd41f57dc2cc6ec149df2
https://doi.org/10.3109/03639049509026641
https://doi.org/10.3109/03639049509026641
Publikováno v:
British Journal of Urology. 71:523-526
Summary— This study was performed to determine urinary sulphate excretion in patients with renal stone disease. Stone formers showed a significantly higher fractional excretion of sulphate than control subjects; 80% of stone formers had fractional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e2cd86b64677cd37bcfb34d4666a5a
https://doi.org/10.1111/j.1464-410x.1993.tb16018.x
https://doi.org/10.1111/j.1464-410x.1993.tb16018.x
Publikováno v:
Medicina. 60(4)
This paper describes experiments designed to test the effect of depot medroxyprogesterone acetate (DMPA) on calcium metabolism of adult ovariectomized rats. The 24 animals were randomly assigned to control or treated groups. Treated rats received 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::818eafac16d493c4fb199e7e56fdcd8f
https://pubmed.ncbi.nlm.nih.gov/11188956
https://pubmed.ncbi.nlm.nih.gov/11188956
Autor:
S, Cornero, R C, Puche
Publikováno v:
Medicina. 60(1)
This study attempts to characterize the health status and diet of prehistoric populations (1,000-2,000 years BP), dwelling at both banks of Parana River, between 29 degrees S and 32 degrees S. The data obtained suggest that these prehistoric populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2641f96ac264e96b39b5f02de230881
https://pubmed.ncbi.nlm.nih.gov/10835707
https://pubmed.ncbi.nlm.nih.gov/10835707
Publikováno v:
Medicina. 59(2)
According to previous pharmacokinetic studies the bioavailability of fluorine (F) from sodium monofluorophosphate (MFP) doubles that of sodium fluoride (NaF). This paper reports a study designed to verify whether the vertebral bone mass increasing ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d61e4b8e16e4a3ab8ac4453c5e76bb6e
https://pubmed.ncbi.nlm.nih.gov/10413893
https://pubmed.ncbi.nlm.nih.gov/10413893
Publikováno v:
Medicina. 59(2)
Sodium monofluorophosphate (MFP) is a drug used in the treatment of primary osteoporosis. Following the intake of MFP, a small fraction of the drug is absorbed intact and forms a complex with alpha 2-macroglobulin (MFP-alpha 2M) inactivating the anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93cfc2d33300dc6d085a6a837318a4ec
https://pubmed.ncbi.nlm.nih.gov/10413892
https://pubmed.ncbi.nlm.nih.gov/10413892
Publikováno v:
Medicina. 57(5)
This paper reports a retrospective study (1979-1995) on 200 patients (154 women and 46 men), 50-101 years old, who received medical attention because of unilateral hip fracture. Nine women and four men fractured twice. In 75% of women and 90% of men,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::564eeb7771d47b2883cf44f882a6001e
https://pubmed.ncbi.nlm.nih.gov/9674220
https://pubmed.ncbi.nlm.nih.gov/9674220
Publikováno v:
Arzneimittel-Forschung. 46(5)
This paper reports a reassessment of the bioavailability of fluoride from monofluorophosphate (MFP, CAS 10163-15-2). It was prompted by recent work from this laboratory reporting that, following an oral dose of MFP, a fraction of the drug appears in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8794f54bf90fc7de155f32aebe910426
https://pubmed.ncbi.nlm.nih.gov/8737641
https://pubmed.ncbi.nlm.nih.gov/8737641
Publikováno v:
Arzneimittel-Forschung. 44(6)
After the administration of an oral dose of 80 mumol/l of NaF (CAS 7681-49-4) to rats, the area under the curve of total plasma fluoride equals 10,200 mumol.min/l. After an oral dose of 80 mumol of monofluorophosphate (MFP/CAS 10,163-15-2), two forms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e288f24bcbd685ca4e37fc0a76bc3456
https://pubmed.ncbi.nlm.nih.gov/8053977
https://pubmed.ncbi.nlm.nih.gov/8053977
Publikováno v:
Arzneimittel-Forschung. 44(5)
This paper reports data indicating that, in the rat, sodium monofluorophosphate (MFP, CAS 10163-15-2) is absorbed without hydrolysis through the stomach. This phenomenon and the fact that MFP binds to plasma globulins produce a prompt increase in pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f4b4fc9d048a50b8cffe269dedcb0c6
https://pubmed.ncbi.nlm.nih.gov/8024641
https://pubmed.ncbi.nlm.nih.gov/8024641