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pro vyhledávání: '"R C Geiger"'
Publikováno v:
Gene Therapy. 13:725-731
Cyclic stretch is known to alter a number of cellular and subcellular processes, including those involved in nonviral gene delivery. We have previously shown that moderate equibiaxial cyclic stretch (10% change in basement membrane area, 0.5 Hz, 50%
Autor:
R C Geiger, Kevin P. Campbell, Kimberly Lane, Scott Budinger, Jonathan C.R. Jones, Meredith Gonzales, Susan B. Hopkinson, David A. Dean, Eduardo Correa-Meyer, Emilia Lecuona, Jacob I. Sznajder
Publikováno v:
Journal of Cell Science. 118:2557-2566
Mechanical ventilation is a valuable treatment regimen for respiratory failure. However, mechanical ventilation (especially with high tidal volumes) is implicated in the initiation and/or exacerbation of lung injury. Hence, it is important to underst
Publikováno v:
Gene therapy
Our lab has previously demonstrated that cytoplasmic trafficking and subsequent nuclear entry of non-viral plasmid DNA can be significantly enhanced through the application of cyclic stretch following transfection in vitro 1,2. Here, we demonstrate t