Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R C Coope"'
Autor:
R C Coope, Eric Lam, Andrew Sunters, J J Gomm, M J Slade, R. C. Coombes, A Assadi-Sabet, M. J. O'Hare, D Roberts-Clark, Carlo Palmieri, A Hanby
Publikováno v:
Journal of Endocrinology. 177:65-81
Keratinocyte growth factor/fibroblast growth factor 7 (KGF/FGF7) is known to be a potent growth factor for mammary cells but its origin, cellular targets and mode of action in the breast are unclear. In this study, we carried out studies to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a026c69a159d6d4f24fa6f0c7b9e13a
https://doi.org/10.1677/joe.0.1770065
https://doi.org/10.1677/joe.0.1770065
Autor:
J. J. Gomm, H C Cox, R. C. Coope, R. C. Coombes, R. Barnard, Sami Shousha, C. Yiangou, G. S. Bansal, N. Groome, J. Walters, C. L. Johnston
Publikováno v:
British Journal of Cancer
Monoclonal antibodies against two epitopes of FGFR-1 have been used to investigate FGFR-1 expression in the normal and neoplastic human breast. Different forms are detected in the different cell types constituting the normal breast. Moreover, breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c1ad78cd8e54075b4d065d0f9f21e5
https://doi.org/10.1038/bjc.1997.573
https://doi.org/10.1038/bjc.1997.573
Publikováno v:
Analytical Biochemistry. 226:91-99
Monoclonal antibodies to epithelial membrane antigen and common acute lymphoblastic leukemia antigen were bound to second antibody-coated magnetic microspheres. These specific antibody/bead complexes were then used to directly isolate purified epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a188bbad2f5c2fe62374f5272cda21
https://doi.org/10.1006/abio.1995.1196
https://doi.org/10.1006/abio.1995.1196
Autor:
A. G. B. Lansdown, S. K. Chander, R. C. Coombes, R. C. Coope, J. J. Gomm, Y. A. Luqmani, N. Gould
Publikováno v:
British Journal of Cancer
Limonene, a monocyclic monoterpene, occurs naturally in orange peel oil. It has been shown to exhibit both chemopreventive and chemotherapeutic activity without toxicity in rodent models. In this study we examined the effect of limonene both at maxim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f177278d314bd70e218402cf13f5b50
https://doi.org/10.1038/bjc.1994.170
https://doi.org/10.1038/bjc.1994.170
Publikováno v:
Experimental cell research. 247(1)
We show that myoepithelial cell basement membrane derived E3 and E8 domains of laminin-1 are capable of polarizing luminal epithelial cells with regard to epithelial membrane antigen localization. This event is dependent on the alpha6 integrin and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dc23ffe91c890f0ee827e799350b8d
https://pubmed.ncbi.nlm.nih.gov/10047469
https://pubmed.ncbi.nlm.nih.gov/10047469
Autor:
G S Bansal, J J Gomm, S K Marsh, D Roberts-Clarke, Richard C. Barnard, Caroline L. Johnston, C Zammit, R. C. Coombes, R C Coope
Publikováno v:
Oncogene. 18(4)
Fibroblast growth factor 8 (FGF8) is an important developmental protein which is oncogenic and able to cooperate with wnt-1 to produce mouse mammary carcinoma. The level of expression of FGF8 mRNA was measured in 68 breast cancers and 24 non-malignan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1245cf6f76e3bdbd2deafb2ad96f4ac9
https://pubmed.ncbi.nlm.nih.gov/10023681
https://pubmed.ncbi.nlm.nih.gov/10023681
Autor:
C L Johnston, R C Coope, C. Yiangou, J J Gomm, P. J. Browne, R. C. Coombes, R Mason, G. S. Bansal
Publikováno v:
Experimental cell research. 234(1)
We have studied separated normal human breast epithelial and myoepithelial cells for the presence of basic fibroblast growth factor (FGF2) and its receptors, both low (heparan sulfate proteoglycans) and high affinity (FGFR1), and for the effects of F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d26197ac46b9a562f85edcea611536
https://pubmed.ncbi.nlm.nih.gov/9223382
https://pubmed.ncbi.nlm.nih.gov/9223382
Autor:
G. S. Bansal, C Yiangou, Sami Shousha, J. J. Gomm, R. C. Coombes, R. C. Coope, C. L. Johnston, P. J. Browne, N. Groome, J. Walters
Publikováno v:
British Journal of Cancer
Acidic fibroblast growth factor (FGF1) and two of its receptors, FGFR1 and FGFR4, were localized in cryostat sections of normal, benign and malignant human breast tissue by immunohistochemistry. Without pretreatment, FGF1 staining was mainly seen in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b3cd9f32990bffe30ca8c38b6fdbd1
http://hdl.handle.net/10044/1/53543
http://hdl.handle.net/10044/1/53543
Autor:
Sami Shousha, C. N. Rees, B. Dagg, R. C. Coope, J. J. Gomm, A. J. Desai, V. Thirunavukkarasu, Paul E. Pace, N. Groome, J. Walters, R. C. Coombes, Simak Ali, YA Luqmani
Publikováno v:
British Journal of Cancer
A variant form of the human oestrogen receptor (ER) mRNA lacking sequences encoded within exon 5 has been described (Fuqua SAW, Fitzgerald SD, Chamness GC, Tandon AK, McDonnell DP, Nawaz Z, O'Malloy BW, McGuire WL 1991, Cancer Res 51: 105-109). We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff761b09c8c1c6f0f51feacc07ea9247
http://hdl.handle.net/10044/1/33450
http://hdl.handle.net/10044/1/33450
Publikováno v:
Journal of cellular physiology. 171(1)
In order to investigate the specific factors controlling the growth of normal breast cell types, purified populations of human breast epithelial and myoepithelial cells from reduction mammoplasties were grown in primary culture in three defined media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85be72de92cd6877d9e8ee692a2c217c
https://pubmed.ncbi.nlm.nih.gov/9119887
https://pubmed.ncbi.nlm.nih.gov/9119887