Zobrazeno 1 - 10
of 127
pro vyhledávání: '"R C, von Borstel"'
Autor:
Oksana Iavorovska, R. C. von Borstel, Carrie L. DeHaan, Barry J. Barclay, Reid W. von Borstel, Ursula G.G. Hennig
Publikováno v:
Environmental and Molecular Mutagenesis. 38:153-158
There is a need for a rapid assay to identify agents that damage mitochondria because the mitochondrion may be an important target for numerous environmental mitotoxins. Certainly at least one chemotherapeutic regimen (CHOP therapy) that includes dox
Autor:
John A. Higgins, R. C. von Borstel
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 402:321-329
Janus carcinogens are carcinogenic agents that, under differing conditions of cell type or dose, can instead act as anticarcinogens. Studies by Haseman and Johnson [J.K. Haseman, F.M. Johnson, Analysis of rodent NTP bioassay data for anticarcinogenic
Autor:
Lucia Liviero, R. C. von Borstel
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 350:287-293
Autor:
Susan P. Stewart, Robin W. Ord, Elizabeth A. Savage, Ursula G.G. Hennig, R. Gary Ritzel, R. C. von Borstel, Grace S.-F. Lee
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 289:97-106
The mut7-1 mutant of Saccharomyces cerevisiae is a cell-division-cycle mutant, exhibiting temperature-sensitive lethality and enhancement of mutator activity with increases in temperature. The base-sequence alterations in mutants arising in a mut7-1
Autor:
A. Richard Morgan, Diane Lee Van On, Grace S.-F. Lee, Karla S. Blonsky, R. C. von Borstel, Elizabeth A. Savage
Publikováno v:
Journal of Molecular Biology. 223:617-626
The base alterations induced by four alkylating agents, methyl methanesulfonate (MMS), ethyl methanesulfonate (EMS), N -nitroso- N -methylurea (MNU), and N -nitroso- N -ethylurea (ENU), have been determined at the URA3 locus in the yeast Saccharomyce
Autor:
K. Sree Ramulu, H. F. Linskens, J. -J. de Klerk, R. C. von Borstel, J. Sybenga, G. J. de Klerk, K. -H. Kogel, A. J. G. van Gastel, A. Ellings, M. Hühn, E. J. J. Zoelen
Publikováno v:
Theoretical and Applied Genetics. 82:117-120
An experimental solution for the Luria–Delbrück fluctuation problem in measuring hypermutation rates
Publikováno v:
Proceedings of the National Academy of Sciences. 96:6847-6849
A cell line harboring all trans-acting elements necessary for hypermutation was transfected with a plasmid harboring the major cis-acting elements plus a green fluorescent protein gene containing a premature chain-termination codon. Transfected cells
Autor:
R. C. von Borstel
Publikováno v:
The Quarterly Review of Biology. 70:250-252
Autor:
R. C. von Borstel
Publikováno v:
The Quarterly Review of Biology. 69:137-139
Autor:
Christopher T. Korch, Lucia Liviero, Qi Wang, P. J. Hastings, Charles Steinberg, Christopher J. Tenove, R. C. von Borstel, Micah A Chrenek, R. Gary Ritzel, Grace S.-F. Lee, Ursula G.G. Hennig, Michael D. Hamilton, Robert Tomaszewski, Elizabeth A. Savage, John A. Higgins
Publikováno v:
Genetics. 148(4)
Mutants of the HIS1 locus of the yeast Saccharomyces cerevisiae are suitable reporters for spontaneous reversion events because most reversions are topical, that is, within the locus itself. Thirteen mutations of his1-1 now have been identified with