Zobrazeno 1 - 10
of 189
pro vyhledávání: '"R C, Zangar"'
Autor:
R C, Zangar, J R, Okita, H, Kim, P E, Thomas, A, Anderson, R J, Edwards, D L, Springer, R T, Okita
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(3)
Calcium channel antagonists are widely prescribed for treatment of hypertension. In this study, we examined whether treatment with the calcium channel antagonists, nicardipine, nifedipine or diltiazem, alters cytochrome P-450 2B or 3A (CYP2B or CYP3A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46d2483f63881e57d3819a3a038fc6a5
https://pubmed.ncbi.nlm.nih.gov/10454523
https://pubmed.ncbi.nlm.nih.gov/10454523
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(4)
The distribution of several cytochrome P-450 (P-450) isoenzymes between proximal tubular (PT) and distal tubular (DT) cells of the rat kidney was determined. Western blot analysis of microsomes prepared from liver and kidney cortical homogenates reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0200ac64d0d84eeeadfe8997434fb1b4
https://pubmed.ncbi.nlm.nih.gov/10101150
https://pubmed.ncbi.nlm.nih.gov/10101150
Publikováno v:
Toxicology and applied pharmacology. 141(1)
Since cytochrome P450 2E1 (CYP2E1) mRNA levels have been reported to be increased during physiological states in which peroxisomes are increased, we examined the effects of the peroxisome proliferator, ciprofibrate (CIPRO), on renal and hepatic CYP2E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f8a04fe9aaeb5d4d601d01e9a1a2c0a
https://pubmed.ncbi.nlm.nih.gov/8917682
https://pubmed.ncbi.nlm.nih.gov/8917682
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(7)
The hepatic and renal toxicity associated with hydrazine treatment has been linked to free radical damage resulting from oxidative metabolism by cytochrome P4502E1 (CYP2E1). Despite this association, there has been little characterization of the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53219285634f58eba3e1d551f7acbc21
https://pubmed.ncbi.nlm.nih.gov/8818569
https://pubmed.ncbi.nlm.nih.gov/8818569
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(7)
Investigation of the posttranscriptional mechanisms involved in the xenobiotic-mediated enhancement of cytochrome P450 2E1 (CYP2E1) expression has been limited by a lack of a functional primary hepatocyte cell culture system. We examined the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3de3403c80e1aeba9a82b97fcab9967
https://pubmed.ncbi.nlm.nih.gov/7587954
https://pubmed.ncbi.nlm.nih.gov/7587954
Autor:
K J, Nikula, R F, Novak, I Y, Chang, A R, Dahl, D A, Kracko, R C, Zangar, S G, Kim, J L, Lewis
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(5)
Carboxylesterases (CEs) in the nasal mucosa metabolize some inhaled esters, including industrially important acrylates and acetates, to toxic acid metabolites that produce site-specific lesions in the nasal epithelium. The metabolic capacity of CEs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c73eb25792e49f5a13ac1dd38049e18f
https://pubmed.ncbi.nlm.nih.gov/7587926
https://pubmed.ncbi.nlm.nih.gov/7587926
Publikováno v:
BioTechniques. 18(3)
Poly(A) tail length is important in the stability and translation of mRNA. We describe procedures for the rapid and reproducible analysis of poly(A) tail length of a single mRNA species contained in a sample of total hepatic RNA. A short 3' fragment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99a7d4ffa802cc0611c6e0d1c61f80e3
https://pubmed.ncbi.nlm.nih.gov/7779397
https://pubmed.ncbi.nlm.nih.gov/7779397
Publikováno v:
Cancer Biomarkers. 2013, Vol. 13 Issue 3, p193-200. 8p.
Publikováno v:
Journal of Proteome Research; Aug2009, Vol. 8 Issue 8, p3937-3943, 7p
Publikováno v:
Toxicological Sciences. 9:659-667
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0158fda712dea85a4d026fbc1fc86a4a
https://doi.org/10.1093/toxsci/9.4.659
https://doi.org/10.1093/toxsci/9.4.659