Zobrazeno 1 - 10
of 19
pro vyhledávání: '"R C, Truchot"'
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 21(7)
1. Simvastatin, a competitive inhibitor of 3-hydroxy-3-methyl glutaryl CoA reductase, lowers the plasma cholesterol level and has been approved for treatment of hyperlipoproteinaemia. 2. Simvastatin has been studied for its effects on hepatic microso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069d7363d40adbbb4a3b5dac2cad3b72
https://pubmed.ncbi.nlm.nih.gov/1776261
https://pubmed.ncbi.nlm.nih.gov/1776261
Publikováno v:
Cellular and molecular biology. 37(8)
The effects of an associated treatment with Ciprofibrate and Simvastatin upon plasma lipid parameters, liver Mixed Function Oxidases enzymes and peroxisomal markers have been studied in male Wistar rats. The association was efficient upon triglycerid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d63f9e300130ef760348568fcb169cd0
https://pubmed.ncbi.nlm.nih.gov/1807786
https://pubmed.ncbi.nlm.nih.gov/1807786
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 15(4)
We compared the ability of two different diets containing 6 per cent of maize oil and 6 per cent of fish oil to modify: firstly the enzyme induction by phenobarbital and secondly the phenobarbital hydroxylation by the liver either in vivo or during i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72b01af63b2fad64de1c0bace856a72
https://pubmed.ncbi.nlm.nih.gov/2088763
https://pubmed.ncbi.nlm.nih.gov/2088763
Publikováno v:
Comptes rendus des seances de la Societe de biologie et de ses filiales. 184(5-6)
The influence of thyroid hormones upon the inductive effects on microsomal enzymes and the hepatic proliferation produced by different fibrates was studied in the male rat. A pharmacological dose of triiodo-L-thyronine significantly lowers the total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34e6cadcb0555c47317ce5a610638748
https://pubmed.ncbi.nlm.nih.gov/2151809
https://pubmed.ncbi.nlm.nih.gov/2151809
Publikováno v:
Fundamental & Clinical Pharmacology. 2:259-265
Summary— The inductive effects of fenofibrate (FF) and phenobarbital (PB) were investigated in male Wistar rats. FF treatment produced an inductive effect on liver weight, cytochrome P450 content, and aniline hydroxylase (AH) and bilirubin UDP-gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1256e6d041c88f27841be9aaa45258
https://doi.org/10.1111/j.1472-8206.1988.tb00637.x
https://doi.org/10.1111/j.1472-8206.1988.tb00637.x
Publikováno v:
Archivos latinoamericanos de nutricion. 33(3)
The influence of two carbamine pesticides i.e., manebe and carbaryl upon the hepatic microsomal enzymes induction in the rat was studied. Both substances, when administered by themselves, affect only slightly liver weight, P 450 cytochrome rates and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c303e076e995e7c14445cd77cc6af4b
https://pubmed.ncbi.nlm.nih.gov/6426422
https://pubmed.ncbi.nlm.nih.gov/6426422
Publikováno v:
Comptes rendus des seances de la Societe de biologie et de ses filiales. 182(3)
The influence of thyroid hormones on microsomal drug metabolizing enzymes was studied in hypothyroid newborn rats and chick embryos. Administration of 3,5,3'-triiodo-L-thyronine strongly decreased the microsomal cytochrome P 450 content in hypothyroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42020884b17b8c66dc76635971c5837f
https://pubmed.ncbi.nlm.nih.gov/2976299
https://pubmed.ncbi.nlm.nih.gov/2976299
Autor:
B, Faye, J, Mounié, L, Champion, J, Magdalou, H, Goudonnet, R C, Truchot, A, Escousse, G, Siest
Publikováno v:
Comptes rendus des seances de la Societe de biologie et de ses filiales. 181(5)
Rats fed a dietary peroxidized fish oil showed an increase in cytochrome P-450 content and ethoxy-coumarin deethylase (ECDE) activity in liver microsomes. Administration of DL-alpha-tocopherol led to different effects according to the extent of the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7463b46e7c076477d62e4e773de8056
https://pubmed.ncbi.nlm.nih.gov/2966657
https://pubmed.ncbi.nlm.nih.gov/2966657
Publikováno v:
Journal de pharmacologie. 17(3)
Male Wistar rats were treated daily for 7 days with clofibrate (250 mg/kg/d), benfluorex (50 mg/kg/d), tiadenol (200 mg/kg/d), nicoclonate (100 mg/kg/d) or hexanicit (50 mg/kg/d). The cytochrome P 450 level and ethoxycoumarin deethylase activity (ECD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d597d45fda6d7e0669c3fbbaa405d1b
https://pubmed.ncbi.nlm.nih.gov/3491930
https://pubmed.ncbi.nlm.nih.gov/3491930
Publikováno v:
Comptes rendus des seances de la Societe de biologie et de ses filiales. 180(4)
Oxidized fish oil (OFO) feeding is followed in the rat by the increase of vitamin A plasmatic level, and modifications of microsomal membranes (decrease of fluorophore ANS fixation). This inhibit the microsomal increase of cytochrome P 450, mixed fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::134531f2125a2554d3c8323b764bcbda
https://pubmed.ncbi.nlm.nih.gov/2948621
https://pubmed.ncbi.nlm.nih.gov/2948621