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pro vyhledávání: '"R C, Sears"'
Autor:
A L, Ostermann, C M, Wunderlich, L, Schneiders, M C, Vogt, M A, Woeste, B F, Belgardt, C M, Niessen, B, Martiny, A C, Schauss, P, Frommolt, A, Nikolaev, N, Hövelmeyer, R C, Sears, P J, Koch, D, Günzel, J C, Brüning, F T, Wunderlich
Publikováno v:
Nature metabolism. 1(3)
Obesity promotes the development of insulin resistance and increases the incidence of colitis-associated cancer (CAC), but whether a blunted insulin action specifically in intestinal epithelial cells (IECs) affects CAC is unknown. Here, we show that
Autor:
R C, Sears, L, Sealy
Publikováno v:
Molecular and Cellular Biology. 14:4855-4871
In this report we demonstrate that C/EBP beta is a major component of three EFII DNA binding complexes, EFIIa, EFIIb, and EFIIc, which we have previously shown to specifically recognize a C/EBP consensus binding site found in the EFII enhancer sequen
Autor:
S. Malempati, R. C. Sears
Publikováno v:
Journal of Investigative Medicine. 53:S105.3-S105
Purpose In this study, we examine the role of c-Myc protein stabilization in 2 pediatric ALL cell lines (REH and Sup-B15), 1 AML cell line (HL-60), and 1 CML cell line (K562). Background Orderly control of c-Myc protein levels is important in maintai