Zobrazeno 1 - 8 of 8 pro vyhledávání: '"R C, Schnur"'
1
Quantitative structure-activity relationships of antitumor guanidinothiazolecarboxamides with survival enhancement for therapy in the 3LL Lewis lung carcinoma model
Autor: R C, Schnur, R J, Gallaschun, D H, Singleton, M, Grissom, D E, Sloan, P, Goodwin, P A, McNiff, A F, Fliri, F M, Mangano, T H, Olson
Publikováno v: Journal of Medicinal Chemistry. 34:1975-1982
Guanidinothiazolecarboxamides (GTCs) are a novel class of antitumor agents found to be systemically active against experimental pulmonary metastases of 3LL Lewis lung carcinoma. A series of substituted benzothiazole GTCs were found to produce enhance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2feb94ce29d3ea90a07710a0257a56f3
https://doi.org/10.1021/jm00111a009
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2
Depletion of the erbB-2 gene product p185 by benzoquinoid ansamycins
Autor: P, Miller, C, DiOrio, M, Moyer, R C, Schnur, A, Bruskin, W, Cullen, J D, Moyer
Publikováno v: Cancer research. 54(10)
Herbimycin A, a benzoquinoid ansamycin, is widely used as an inhibitor of tyrosine kinases. We have examined the effects of herbimycin A and several analogues on p185, the tyrosine kinase encoded by the erbB2 gene in human breast cancer cells. Exposu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3c093862569312b57e111c52b4e47f7
https://pubmed.ncbi.nlm.nih.gov/7909494
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