Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R C, Pohland"'
Autor:
T. P. Clark, K. J. Freise, J. A. Abbott, R. C. Pohland, M. C. Savides, D. A. Wilkie, G. C. Newbound
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 35:35-43
Previous studies have demonstrated that a single, topical application of a novel, long-acting transdermal fentanyl solution provides analgesic fentanyl concentrations for at least 4 days. The objective of this study was to describe the margin of safe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375a388f1bd3028c9159b05af4dec5ce
https://doi.org/10.1111/j.1365-2885.2012.01410.x
https://doi.org/10.1111/j.1365-2885.2012.01410.x
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 35
Previous studies have demonstrated that a single, topical application of a novel, long-acting transdermal fentanyl solution provides analgesic fentanyl concentrations for at least 4 days. The objective of this study was to describe the margin of safe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c42d0936f45a055348062627c81f008a
https://pubmed.ncbi.nlm.nih.gov/22731774
https://pubmed.ncbi.nlm.nih.gov/22731774
Publikováno v:
Biopharmaceutics & Drug Disposition. 15:137-150
Tissue distribution studies, utilizing whole-body autoradiography and organ dissection techniques, were conducted in male Fischer 344 rats following the oral administration of 14C-dapoxetine HCl, a potent serotonin reuptake inhibitor. The preliminary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c474c092edce0f47f9d0f6d254256282
https://doi.org/10.1002/bdd.2510150206
https://doi.org/10.1002/bdd.2510150206
Publikováno v:
Drug Development and Industrial Pharmacy. 16:899-920
A water-in-oil microemulsion was prepared to deliver cetyl alchohol [I] octyl dimethyl PABA or Padimate-O [II] in vitro using human and hairless mouse skin. A standard Franz diffusion cell and a microsectiong cryostat microtome were used to quantify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cffc7cece5d0cdcfb4adabdba671b03
https://doi.org/10.3109/03639049009114917
https://doi.org/10.3109/03639049009114917
Autor:
R C, Pohland, N R, Bernhard
Publikováno v:
Journal of forensic sciences. 42(5)
Antemortem serum and postmortem serum and tissues were evaluated to determine if postmortem redistribution of the antidepressant, fluoxetine (Prozac) and its major active metabolite, norfluoxetine, occurred in dogs following oral administration of fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41dcc7fd9c23346687796b216f10037c
https://pubmed.ncbi.nlm.nih.gov/9304827
https://pubmed.ncbi.nlm.nih.gov/9304827
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(9)
LY255582 is a phenylpiperidine opioid antagonist under development as an appetite suppressant and for the treatment of obesity. Female beagles were administered [14C]LY255582 at dosages of 0.72 mg/kg intravenously or 7.2 mg/kg orally. The majority (5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c4a9580aaa484c1b927a693ada47e5f
https://pubmed.ncbi.nlm.nih.gov/8565781
https://pubmed.ncbi.nlm.nih.gov/8565781
Autor:
S H, Chay, R C, Pohland
Publikováno v:
Journal of pharmaceutical sciences. 83(9)
Quantitative whole-body autoradiography (QWBA) was evaluated and compared to tissue dissection/liquid scintillation counting (TD/LSC) techniques by determining the tissue distribution of radiocarbon in rats following iv administration of the antibiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c41f8745a75f6f64782c42794fddd0f
https://pubmed.ncbi.nlm.nih.gov/7830246
https://pubmed.ncbi.nlm.nih.gov/7830246
Autor:
R. C. Pohland, M. T. Vavrek
Publikováno v:
Teratology. 44(1)
The placental transfer of orally administered ameltolide was evaluated to confirm embryonic exposure in the rat developmental toxicity study (Higdon et al., '91). Dissection techniques were used to determine the amount of total radiocarbon that trave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0cda14dc1343975c82ccfb1c36827e
https://pubmed.ncbi.nlm.nih.gov/1957262
https://pubmed.ncbi.nlm.nih.gov/1957262
Publikováno v:
Journal of Animal Science. 55:145-152
Studies were conducted to determine the absorption and metabolic fate of 3H-estradiol-17 beta-glucuronide (3H-E2-G) in swine. The conjugate, 3H-E2-G (48.7 x 10(6) DPM, 45.5 Ci/mmol), was injected into ligated 15-cm sections of duodenum, proximal jeju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72168f214e5232e8cf92e8cac6693f8a
https://doi.org/10.2527/jas1982.551145x
https://doi.org/10.2527/jas1982.551145x
Publikováno v:
Journal of Animal Science. 55:124-134
One minute after instillation of 14C-estradiol-17 beta (14C-E2 17 beta) into selected sections of the gastrointestinal tract of swine, radioactive estradiol metabolites were present in blood collected from the portal and jugular veins. Ether was used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3216bff8e23a9fb3c85d357efa5bfd2
https://doi.org/10.2527/jas1982.551124x
https://doi.org/10.2527/jas1982.551124x