Zobrazeno 1 - 10
of 39
pro vyhledávání: '"R C, Mohs"'
Autor:
R. C. Mohs
Publikováno v:
Genes, Brain and Behavior. 4:129-133
This paper describes the natural history of the clinical syndrome of Alzheimer's disease (AD) including the cognitive deficit, the neuropsychiatric symptoms, impact on daily functioning, risk factors, medical complications and impact on the use of he
Publikováno v:
Archives of Clinical Neuropsychology. 17:611-623
Publikováno v:
Neurology. 68(13)
Objective: To investigate the efficacy and safety of the positive α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid modulator LY451395 in patients with mild to moderate Alzheimer disease (AD) (Mini-Mental State Examination scores 14 to 26).Metho
Autor:
J M, Silverman, C M, Smith, D B, Marin, J, Schmeidler, S, Birstein, M, Lantz, K L, Davis, R C, Mohs
Publikováno v:
International journal of geriatric psychiatry. 15(7)
Studies of the familial aggregation of Alzheimer's disease have primarily used samples ascertained from tertiary care clinics which may not be representative of many AD patients, for example those residing at geriatric nursing homes. Survival analysi
Publikováno v:
American journal of medical genetics. 88(4)
Recent evidence for mitochondrial mutations associated with Alzheimers disease (AD) suggests the possibility of maternal transmission of this illness. We investigated this hypothesis by examining, in a variety of ways, the risk of a primary progressi
Autor:
K F, Sheu, A M, Brown, V, Haroutunian, B S, Kristal, H, Thaler, M, Lesser, R N, Kalaria, N R, Relkin, R C, Mohs, L, Lilius, L, Lannfelt, J P, Blass
Publikováno v:
Annals of neurology. 45(1)
The mitochondrial alpha-ketoglutarate dehydrogenase complex (KGDHC) is deficient in Alzheimer's disease (AD). The DLST gene encodes the core, dihydrolipoyl succinyltransferase (DLST) component of KGDHC, and recent reports indicate an association betw
Autor:
A, Heyman, G G, Fillenbaum, K A, Welsh-Bohmer, M, Gearing, S S, Mirra, R C, Mohs, B L, Peterson, C F, Pieper
Publikováno v:
Neurology. 51(1)
To study the relation between cerebral infarction and clinical and neuropsychologic manifestations in patients with autopsy-proven Alzheimer's disease (AD) enrolled in the Consortium to Establish a Registry for Alzheimer's Disease (CERAD).Prior studi
Publikováno v:
Archives of internal medicine. 158(9)
Donepezil hydrochloride (Aricept) is a selective acetylcholinesterase inhibitor developed for the treatment of Alzheimer disease. This phase 3 study was 1 of 2 pivotal trials undertaken to establish the efficacy and safety of using donepezil in patie
Autor:
P J, Whitehouse, J M, Orgogozo, R E, Becker, S, Gauthier, M, Pontecorvo, H, Erzigkeit, S, Rogers, R C, Mohs, N, Bodick, G, Bruno, P, Dal-Bianco
Publikováno v:
Alzheimer disease and associated disorders. 11
Autor:
R C, Mohs, D, Knopman, R C, Petersen, S H, Ferris, C, Ernesto, M, Grundman, M, Sano, L, Bieliauskas, D, Geldmacher, C, Clark, L J, Thal
Publikováno v:
Alzheimer disease and associated disorders. 11
The cognitive assessment protocol of the Alzheimer's Disease Cooperative Study (ADCS) was designed to evaluate the reliability and validity of cognitive assessment measures that might be valuable additions to the Alzheimer's Disease Assessment Scale