Zobrazeno 1 - 10 of 11 pro vyhledávání: '"R C, Melcangi"'
1
Liver X receptors, nervous system, and lipid metabolism
Autor: G, Cermenati, E, Brioschi, F, Abbiati, R C, Melcangi, D, Caruso, N, Mitro
Publikováno v: Journal of endocrinological investigation. 36(6)
Lipids in the nervous system are represented by cholesterol and phospholipids as constituents of cell membranes and, in particular, of myelin. Therefore, lipids are finely regulated to guarantee physiological functions. In the central nervous system,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45f83a4460a042ab488718deb5221d59
https://pubmed.ncbi.nlm.nih.gov/23609963
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2
Neuroprotective Effects of Progesterone in Chronic Experimental Autoimmune Encephalomyelitis
Autor: S, Giatti, D, Caruso, M, Boraso, F, Abbiati, E, Ballarini, D, Calabrese, M, Pesaresi, R, Rigolio, M, Santos-Galindo, B, Viviani, G, Cavaletti, L M, Garcia-Segura, R C, Melcangi
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Observations so far obtained in experimental autoimmune encephalomyelitis (EAE) have revealed the promising neuroprotective effects exerted by progesterone (PROG). The findings suggest that this neuroactive steroid may potentially represent a therape
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d1c90038cac88bc2286998fd365092c7
http://hdl.handle.net/10261/61362
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3
Oestrogens, via transforming growth factor alpha, modulate basic fibroblast growth factor synthesis in hypothalamic astrocytes: in vitro observations
Autor: M, Galbiati, L, Martini, R C, Melcangi
The data presented here show that, in cultures of type 1 astrocytes obtained from the hypothalamus of neonatal female rat, 17beta-oestradiol is able to increase both the mRNA and the protein levels of basic fibroblast growth factor (bFGF). In particu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cd18bf616ee0e1b809e90f29769bcdae
http://hdl.handle.net/2434/28947
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4
Formation and effects of neuroactive steroids in the central and peripheral nervous system
Autor: R C, Melcangi, V, Magnaghi, M, Galbiati, L, Martini
Publikováno v: International review of neurobiology. 46
This chapter summarizes several observations that emphasize the importance of neuroactive steroids in the physiology of the central and peripheral nervous systems. A new, and probably important, concept is emerging: Neuroactive steroids not only modi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::83cd6cc2492fd1eee9a50f35ba6298f1
https://pubmed.ncbi.nlm.nih.gov/11599299
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6
Hypothalamic transforming growth factor beta1 and basic fibroblast growth factor mRNA expression is modified during the rat oestrous cycle
Autor: M, Galbiati, V, Magnaghi, L, Martini, R C, Melcangi
Publikováno v: Journal of neuroendocrinology. 13(6)
The present observations show that the mRNA levels of two growth factors, previously described to be involved in the control of neurones synthesizing the luteinizing hormone releasing hormone (LHRH) [i.e. transforming growth factor beta1 (TGFbeta1) a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3da6297620ca9d56276a6bf70ed4c445
https://pubmed.ncbi.nlm.nih.gov/11412334
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8
Progesterone derivatives are able to influence peripheral myelin protein 22 and P0 gene expression: possible mechanisms of action
Autor: R C, Melcangi, V, Magnaghi, I, Cavarretta, I, Zucchi, P, Bovolin, D, D'Urso, L, Martini
Publikováno v: Journal of neuroscience research. 56(4)
The present study has analyzed the effect of progesterone and its derivatives (dihydroprogesterone and tetrahydroprogesterone) on the gene expression of the peripheral myelin protein 22 utilizing in vivo and in vitro models. The data obtained indicat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b14f431b0c2ed4c5189e2a96fe061001
https://pubmed.ncbi.nlm.nih.gov/10340743
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9
Is the 5 alpha-reductase-3 alpha-hydroxysteroid dehydrogenase complex associated with the myelin in the peripheral nervous system of young and old male rats?
Autor: R C, Melcangi, F, Celotti, P, Castano, L, Martini
Publikováno v: Endocrine regulations. 26(3)
The formation of the 5 alpha-reduced metabolites of testosterone, 5 alpha-androstan-17 beta-ol-3-one (dihydroxytestosterone, DHT) and 5 alpha-androstan-3 alpha, 17 beta-diol (3 alpha-diol) was evaluated in sciatic nerve fragments and homogenates and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::99e4984356b27cd7e11d3d814c5c562f
https://pubmed.ncbi.nlm.nih.gov/1308154
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10
The 5 alpha-reductase in the brain: molecular aspects and relation to brain function
Autor: F, Celotti, R C, Melcangi, L, Martini
Publikováno v: Frontiers in neuroendocrinology. 13(2)
All the classes of hormonal steroids physiologically produced in the body (androgens, estrogens, progestagens, and corticosteroids) are able to exert important effects on the brain, but the mechanisms of their actions are not always well understood.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::239b9d970e2ae70b195d5a7ef41273bc
https://pubmed.ncbi.nlm.nih.gov/1468601
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