Zobrazeno 1 - 10
of 55
pro vyhledávání: '"R C, Knapp"'
Publikováno v:
Methods in molecular medicine. 39
Tumor markers are used for multiple purposes in clinical care, including screening asymptomatic subjects, differential diagnosis of symptomatic patients, treatment planning, prognosis during and immediately following treatment, and monitoring for rec
Publikováno v:
Radiotherapy and Oncology. 23:150-159
Monoclonal antibody (mAb) OC125 detects the cell surface-antigen CA 125, which is expressed in more than 80% of epithelial ovarian cancers but not in normal adult ovaries. Its high specificity and binding affinity makes OC125 a potential candidate fo
Publikováno v:
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 13(5)
In this case, rising longitudinal levels of CA125 were significant in the detection of peritoneal papillary serous carcinoma, and led to the indication for surgery. Rising longitudinal CA125 has been shown to be important in the detection of ovarian
Publikováno v:
Journal of Clinical Oncology. 8:1938-1940
Publikováno v:
Cancer. 76
Stored samples from women in the Stockholm screening study were reassayed for CA125II (Centocor, Malvern, PA) and OVX1. The postmenopausal women older than age 50 without ovarian cancer were randomly split into a training set to develop a screening t
Autor:
M G, Muto, W R, Welch, S C, Mok, C A, Bandera, P M, Fishbaugh, S W, Tsao, C C, Lau, H M, Goodman, R C, Knapp, R S, Berkowitz
Publikováno v:
Cancer research. 55(3)
Histopathological evidence suggests that papillary serous carcinoma of the peritoneum (PSCP) may be multifocal in origin. Utilizing a PCR based method to detect tandem repeat polymorphisms in formalin fixed tissue, loss of heterozygosity at eight loc
Autor:
S C, Mok, D A, Bell, R C, Knapp, P M, Fishbaugh, W R, Welch, M G, Muto, R S, Berkowitz, S W, Tsao
Publikováno v:
Cancer research. 53(7)
The mutation of K-ras protooncogene was examined in 44 cases of borderline ovarian epithelial tumors and 18 cases of invasive ovarian carcinomas. In borderline tumors, K-ras mutations are a common feature, having been found in 21 of 44 cases (48%). T
Publikováno v:
Cancer research. 52(18)
Ovarian cancers are often diagnosed at a late stage, after the cancer cells have spread to extraovarian sites. Failure to diagnose these tumors earlier may reflect the lack of symptoms and the need for a sensitive, reliable screening test. Alternativ
Publikováno v:
Obstetrics and gynecology. 80(1)
Detection of ovarian cancer at an early stage should reduce the mortality associated with this disease. Through the Stockholm Population Registry, 5550 apparently healthy women were enrolled in a study designed in part to define the use of the CA 125
Autor:
S W, Tsao, C H, Mok, K, Oike, M, Muto, H M, Goodman, E E, Sheets, R S, Berkowitz, R C, Knapp, C C, Lau
Publikováno v:
Anticancer research. 11(6)
Previous reports have shown that one copy of the chromosome 17 was frequently lost in human ovarian cancers (1). The position of the allelic deletion has not been mapped and involvement of p53 gene has not been determined. In this study, we have show