Zobrazeno 1 - 10
of 20
pro vyhledávání: '"R C, Kammerer"'
Publikováno v:
Journal of Steroid Biochemistry. 36:659-666
Fluoxymesterone, an anabolic steroid, is metabolized in man primarily by 6 beta-hydroxylation, 4-ene-reduction, 3-keto-reduction, and 11-hydroxy-oxidation. These pathways of metabolism are suggested by the positive identification of 4 metabolites and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f386acfaf6162feb7d459b16bf9771c
https://doi.org/10.1016/0022-4731(90)90185-u
https://doi.org/10.1016/0022-4731(90)90185-u
Autor:
R. C. Kammerer, Lampe Ma
Publikováno v:
Xenobiotica. 20:1269-1280
1. The metabolism of methapyrilene (MPH) by rat, hamster and mouse liver microsomes in vitro was investigated together with the binding of 14C-MPH to calf thymus DNA after metabolic activation. 2. Both quantitative and qualitative differences in MPH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce41cb32ddcb2dee0b7710b07ae1b50a
https://doi.org/10.3109/00498259009046626
https://doi.org/10.3109/00498259009046626
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 20:833-841
Xylamine [N-(2-chloroethyl)-N-ethyl-2-methylbenzylamine], an irreversible inhibitor of neuronal norepinephrine uptake, has been synthesized with tritium incorporated in the aromatic nucleus. Initially, 2-methylbenzyl bromide was nonselectively mono-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf5038ddb7f7a9642e49922d64ec1c67
https://doi.org/10.1002/jlcr.2580200708
https://doi.org/10.1002/jlcr.2580200708
Publikováno v:
Clinical Chemistry. 33:319-327
The equipment, methods, logistics, and results of doping-control analyses for the 1984 Los Angeles Olympic Games are discussed in this article. Within 15 days, 1510 different urine specimens underwent 9440 screening analyses by a combination of gas c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687d8643ddc529668a89161cfdaa9144
https://doi.org/10.1093/clinchem/33.2.319
https://doi.org/10.1093/clinchem/33.2.319
Autor:
Debra A. Schmitz, R. C. Kammerer
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 18(9)
1. In vitro metabolism of methaphenilene (MFN) and pyribenzamine (PBZ) was compared to that of methapyriline (MPH) in rat, because chronic treatment with MPH causes cancer in rats, whereas MFN and PBZ cause no cancer. 2. G.l.c. and mass spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db58f10b291933ee177bc5458b3d863a
https://pubmed.ncbi.nlm.nih.gov/3227706
https://pubmed.ncbi.nlm.nih.gov/3227706
Autor:
D. A. Schmitz, R. C. Kammerer
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 16(7)
Metabolism of lidocaine in rabbit liver 9000 g supernatant fraction was examined. A capillary g.l.c. assay was developed to separate seven known metabolites of lidocaine, and all seven metabolites were identified in extracts of incubations of lidocai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12421fc9cc40f114241feabf8e8516d
https://pubmed.ncbi.nlm.nih.gov/3751122
https://pubmed.ncbi.nlm.nih.gov/3751122
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 6(4)
Phenylacetone, phenyl-2-butanone, and 3-methyl-1-phenyl-2-butanone were incubated with rabbit liver 9000g supernatant fraction for 30 and 60 min to yield primarily the alcohols, plus small amounts of 1,2-glycols and ketols (2-one-1-ols). Phenylaceton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aabcec3c1485362f5f588135883d37b6
https://pubmed.ncbi.nlm.nih.gov/28919
https://pubmed.ncbi.nlm.nih.gov/28919
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 11(1)
Four products of the in vitro oxidative metabolism of the piperidine ring of phencyclidine, 5-(1-phenylcyclohexylamino)valeraldehyde, V; N-(1-phenylcyclohexyl)-1,2,3,4-tetrahydropyridine, VIII; 5-(1-phenylcyclohexylamino)valeric acid, VII; and 1-phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3556eaaa9909ef58c25758d342d4d5ef
https://pubmed.ncbi.nlm.nih.gov/6132795
https://pubmed.ncbi.nlm.nih.gov/6132795
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 9(3)
The in vitro metabolism of phencyclidine by rabbit liver 9000g supernatant fraction produces primarily three known hydroxylated metabolites-namely, 4-phenyl-4-piperidinocyclohexanol, 4-(4'-hydroxypiperdino)-4phenylcyclohexanol, and 1-(1-phenylcyclohe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26a499e9480a9865b4f279a019a4084d
https://pubmed.ncbi.nlm.nih.gov/6113940
https://pubmed.ncbi.nlm.nih.gov/6113940
Publikováno v:
Journal of medicinal chemistry. 22(4)
Eight benzylamine analogues of bretylium were synthesized, including N-(2-chloroethyl)-N-ethyl-2-methylbenzylamine (5), and evaluated as inhibitors of accumulation of norepinephrine and dopamine in rat brain homogenates. All compounds gave an I50 val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c712fb5dd194bb2e0b952664b95f9f
https://pubmed.ncbi.nlm.nih.gov/430475
https://pubmed.ncbi.nlm.nih.gov/430475