Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R C, Franson"'
Publikováno v:
Clinical and Experimental Nephrology. 3:250-253
Background. Glomerulosclerosis is a characteristic feature in the subtotal (5/6) nephrectomy, remnant kidney model in the rat. It is postulated that oxidative stress from this renal mass reduction may induce the glomerular and tubular injury leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff4a0ccf18fd863723d27fe3fa7fa5fc
https://doi.org/10.1007/s101570050043
https://doi.org/10.1007/s101570050043
Autor:
M Bartolf, R C Franson
Publikováno v:
Journal of Lipid Research, Vol 27, Iss 1, Pp 57-63 (1986)
Homogenates of bovine adrenal medullae hydrolyzed exogenous sphingomyelin at 4.3 +/- 1.6 nmol X mg-1 X min-1 and 97% of this sphingomyelinase activity was sedimentable at 110,000 g. The sphingomyelinase had a broad pH optimum centered at pH 7. Enzyma
Externí odkaz:
https://doaj.org/article/db23c581c7b5459b8eafb52c114ee349
Autor:
A.H. Lewin, Kenneth M. Tramposch, Paul L. Stanley, R C Franson, D O Nettleton, F I Carroll, Steiner Stephen A
Publikováno v:
Biochemical and Biophysical Research Communications. 189:272-279
Activation of a phospholipase A2 (PLA2) is a key step in the production of precursors for the biosynthesis of lipid mediators of inflammation. Inhibition of this enzyme could result in the suppression of three important classes of inflammatory lipids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cc3988a6aabd82b3a9fe473de1de57
https://doi.org/10.1016/0006-291x(92)91554-4
https://doi.org/10.1016/0006-291x(92)91554-4
Publikováno v:
Clinical Chemistry. 36:198-200
We measured phospholipase A2 (PLA2; EC 3.1.1.4) activity in normal and uremic plasma, using [1-14C]oleate-labeled autoclaved Escherichia coli as substrate. Hydrolysis of bacterial phospholipid by crude plasma from both groups was optimal at pH 5.5, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2fcdc8695240a2f0155566cba3cd862
https://doi.org/10.1093/clinchem/36.2.198
https://doi.org/10.1093/clinchem/36.2.198
Autor:
R C, Franson, M D, Rosenthal
Publikováno v:
Advances in experimental medicine and biology.
Previously we reported that PGBx, a prostaglandin oligomer with anti-inflammatory activity, inhibited 14 kDa phospholipase A2 (PLA2) activity and blocked arachidonic acid mobilization in prelabeled human neutrophils (Biochim. Biophys. Acta 1006:272-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::668c4cac1a6e1ade7af1ed4442e438f4
https://pubmed.ncbi.nlm.nih.gov/9547578
https://pubmed.ncbi.nlm.nih.gov/9547578
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 11(1)
Clinical and experimental evidence suggest that haemodialysis (HD) procedure is an inflammatory process. For the production of proinflammatory lipid mediators in many inflammatory reactions, the release of arachidonic acid by phospholipase A2 (PLA2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4202ee02abb78ea833df4c864f53bf1
https://pubmed.ncbi.nlm.nih.gov/8649616
https://pubmed.ncbi.nlm.nih.gov/8649616
Autor:
K M, Tramposch, F H, Chilton, P L, Stanley, R C, Franson, M B, Havens, D O, Nettleton, L B, Davern, I M, Darling, R J, Bonney
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(2)
The effect of a phospholipase A2 (PLA2) inhibitor on leukotriene, prostaglandin and platelet activating factor (PAF) biosynthesis in isolated cells and in vivo was determined. BMS-181162, [4(3'-carboxyphenyl)-3,7-dimethyl-9(2",6",6"-trimethyl-1"- cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95826377cee77a81e5c2b75a32d8d949
https://pubmed.ncbi.nlm.nih.gov/7965805
https://pubmed.ncbi.nlm.nih.gov/7965805
Publikováno v:
Clinical chemistry. 36(2)
We measured phospholipase A2 (PLA2; EC 3.1.1.4) activity in normal and uremic plasma, using [1-14C]oleate-labeled autoclaved Escherichia coli as substrate. Hydrolysis of bacterial phospholipid by crude plasma from both groups was optimal at pH 5.5, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e6d18278129a63958d8b938322478ce
https://pubmed.ncbi.nlm.nih.gov/2406039
https://pubmed.ncbi.nlm.nih.gov/2406039
Publikováno v:
Agents and Actions. 25:394-400
The interaction of retinoids and flavonoids with phospholipases A2 (PLA2) was studied to assess the mechanism of inhibition. Retinoids, such as retinal, retinol, retinoic acid and retinol acetate, and flavonoids, such as quercetin, rutin, morin and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e9af624ec0afba3a28c7a1fd639a39
https://doi.org/10.1007/bf01965048
https://doi.org/10.1007/bf01965048