Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R C, Billinghurst"'
Autor:
C. W. Mc Ilwraith, V. Baker, Rick M. Arthur, J. A. Blea, R. C. Billinghurst, David D. Frisbie
Publikováno v:
Equine Veterinary Journal. 42:643-651
Summary Reason for performing study: Biomarkers have shown some in vivo promise for the detection of musculoskeletal injuries, but further study to assess biomarker levels in clinical orthopaedic disease is required. Objective: To assess 7 serum biom
Publikováno v:
Osteoarthritis and Cartilage. 11(10):760-769
Objective: To identify metabolic biomarkers that can be evaluated in serum for monitoring the effects of exercise on skeletal development in mammals. Design: Sera of foals from three groups (box-stall rest, pasture and training) were serially collect
Autor:
A R Poole, Ann B. Millar, L Armstrong, David R Thickett, J P Mansell, M Ionescu, E Hoyle, R C Billinghurst
Publikováno v:
Scopus-Elsevier
Pulmonary fibrosis is a well-recognized feature of acute respiratory distress syndrome (ARDS). Using immunoassays of bronchoalveolar lavage (BAL), fluid we investigated the synthesis of type I procollagen (PICP) and type I/II collagen degradation pro
Publikováno v:
Equine veterinary journal. 42(7)
Biomarkers have shown some in vivo promise for the detection of musculoskeletal injuries, but further study to assess biomarker levels in clinical orthopaedic disease is required.To assess 7 serum biomarkers for the detection of musculoskeletal injur
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 151
Autor:
L, Dahlberg, R C, Billinghurst, P, Manner, F, Nelson, G, Webb, M, Ionescu, A, Reiner, M, Tanzer, D, Zukor, J, Chen, H E, van Wart, A R, Poole
Publikováno v:
Arthritis and rheumatism. 43(3)
To examine whether type II collagen cleavage by collagenase and loss of proteoglycan are excessive in human osteoarthritic (OA) articular cartilage compared with nonarthritic articular cartilage, and whether this can be inhibited by a selective synth
Autor:
R C, Billinghurst, W, Wu, M, Ionescu, A, Reiner, L, Dahlberg, J, Chen, H, van Wart, A R, Poole
Publikováno v:
Arthritis and rheumatism. 43(3)
To compare interleukin-1alpha (IL-1alpha)-induced degradation of nasal and articular cartilages in terms of proteoglycan loss and type II collagen cleavage, denaturation, and release; to examine the temporal relationship of these changes; and to inve
Autor:
R, Stoop, P M, van der Kraan, P, Buma, A P, Hollander, R C, Billinghurst, A R, Poole, W B, van den Berg
Publikováno v:
Arthritis and rheumatism. 42(11)
Degradation of type II collagen during osteoarthritis (OA) is thought to be the key process leading to cartilage destruction. In this study, we investigated whether OA is characterized by either a generalized breakdown of the collagenous network or a
Autor:
Leif Dahlberg, H. E. Van Wart, C Rorabeck, A R Poole, R Bourne, A. Reiner, Jian Jeffrey Chen, O Diekmann, P Mitchell, Mirela Ionescu, J Hambor, R C Billinghurst, Harald Tschesche
We demonstrate the direct involvement of increased collagenase activity in the cleavage of type II collagen in osteoarthritic human femoral condylar cartilage by developing and using antibodies reactive to carboxy-terminal (COL2-3/4C(short)) and amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb6917c90857aab750365801053e226
https://europepmc.org/articles/PMC507973/
https://europepmc.org/articles/PMC507973/
Publikováno v:
Equine veterinary journal. 27(3)
Summary Synovial fluid (SF) was collected at 2, 12 and 26 h post racing from 5 Thoroughbred horses (6 joints) with degenerative joint disease. The effects of serial arthrocentesis on SF TNFα levels were controlled for by testing, in parallel, site-