Zobrazeno 1 - 10
of 164
pro vyhledávání: '"R Burgada"'
Publikováno v:
Journal of Alloys and Compounds. :89-92
This paper discusses biokinetic and decorporation data in animals after contamination by Pu and Np in order to develop new experimental approaches for improving the efficacy of human treatment. Only contamination by intravenous or intramuscular injec
Autor:
R. Burgada, Théodorine Bailly
Publikováno v:
Comptes Rendus de l'Académie des Sciences - Series IIC - Chemistry. 1:241-245
Resume Le 3,4,3 LI 1,2 HOPO est un ligand tres efficace pour eliminer les actinides de l'organisme ayant ete contamine par une procedure simulant un accident nucleaire (Pu, Am, Th, UO 2 ). Le developpement de ce ligand etait compromis par une procedu
Publikováno v:
International Journal of Radiation Biology. 71:613-621
Diethylenetriamine pentaacetic acid (DTPA) has been tested with 8 other new chelators for neptunium decorporation after systemic contamination in the rat. The ligands were injected intravenously at a dosage of 30 mumol kg-1 and the animals killed 24
Autor:
R. Burgada, Théodorine Bailly
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 115:39-42
The reaction of spermine with aromatic aldehyde leads to an equilibrated system between the bis imine form 1' and the hexahydropyrimidine form 1. In contrary the formaldehyde adduct of spermine exist only on the hexahydropyrimidine form 9. 1–1' is
Publikováno v:
International Journal of Radiation Biology. 70:109-114
The effect of a siderophore analogue 3,4,3-LIHOPO has been investigated in rat after intramuscular injection of 238Pu, 239Pu and 241Am simulating puncture wounds. Various treatment regimens were used to remove the radioactivity from its injection sit
Autor:
R. Burgada, Théodorine Bailly
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 103:125-132
The spirophosphoranes 1 to 4, 6 and 7 bearing a P—H bond have been condensed with tetraethyl (z) or tetra methyl (x) ethenylidene bis phosphonate by a Michael type addition reaction. The resulting compounds: Spirophosphoranes-bis phosphonates 1x, 3
Autor:
R. Burgada, Kenneth N. Raymond, M.J. Pearce, J.C. Moody, I. Wilson, G.N. Stradling, P.W. Durbin, S.A. Gray
Publikováno v:
Radiation Protection Dosimetry. 53:319-322
The comparative efficacies of treatment with 3,4,3-LIHOPO and DTPA have been investigated in the rat after their subcutaneous and intramuscular injection. Commencement of treatment was delayed 30 min, 6 h or 1 d and the animals killed at 7 d. Under a
Autor:
T. Bailly, J. L. Poncy, Y. Leroux, R. Burgada, Roland Masse, François Paquet, P.W. Durbin, G. Rateau, Kenneth N. Raymond
Publikováno v:
Radiation Protection Dosimetry. 53:323-326
The ability of 3,4,3-LIHOPO, used at a dosage of 3 μmol.kg −1 of body weight, has been tested in Sprague-Dawley rats for reducing the retention of plutonium after inhalation of 238 Pu-TBP. The comparison was made with DTPA, the reference substance
Autor:
Théodorine Bailly, R. Burgada
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 86:217-228
Tetraethyl ethenylidene bis phosphonate can undergo facile Michael type addition reaction with amines, alcohols, water, aminoacid and spirophosphoranes bearing a P[sbnd]H bond. The stability of these compounds was investigated and the reversibility o
Publikováno v:
International Journal of Radiation Biology. 63:785-793
Chelating agents were tested for removal of simultaneously injected Pu-238 and Am-241 from the rat. The effectiveness of early single chelate injections of Pu-238 retention in tissues decreased in the order 3,4,3-LIHOPODFO-HOPODTPADTPA-DX, and for Am